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Difference between revisions of "Inflammatory skin disorders"
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→Psoriasis
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*Other considerations: | *Other considerations: | ||
**Drug-induced psoriasis.<ref>{{Cite journal | last1 = Milavec-Puretić | first1 = V. | last2 = Mance | first2 = M. | last3 = Ceović | first3 = R. | last4 = Lipozenčić | first4 = J. | title = Drug induced psoriasis. | journal = Acta Dermatovenerol Croat | volume = 19 | issue = 1 | pages = 39-42 | month = Mar | year = 2011 | doi = | PMID = 21489366 }}</ref> | **Drug-induced psoriasis.<ref name=pmid21489366>{{Cite journal | last1 = Milavec-Puretić | first1 = V. | last2 = Mance | first2 = M. | last3 = Ceović | first3 = R. | last4 = Lipozenčić | first4 = J. | title = Drug induced psoriasis. | journal = Acta Dermatovenerol Croat | volume = 19 | issue = 1 | pages = 39-42 | month = Mar | year = 2011 | doi = | PMID = 21489366 }}</ref> | ||
====Clinical==== | ====Clinical==== | ||
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Common locations:<ref name=Ref_PCPBoD8_603>{{Ref PCPBoD8|603}}</ref> | Common locations:<ref name=Ref_PCPBoD8_603>{{Ref PCPBoD8|603}}</ref> | ||
*Knees, elbows, scalp, glands penis. | *Knees, elbows, scalp, glands [[penis]]. | ||
===Microscopic=== | ===Microscopic=== | ||
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*Parakeratosis. | *Parakeratosis. | ||
*Dilated vessels in superficial dermis (give rise to ''Auspitz sign''). | *Dilated vessels in superficial dermis (give rise to ''Auspitz sign''). | ||
*Spongiform pustules = | *Spongiform pustules = [[PMN]]s in stratum spinosum. | ||
*PMNs in parakeratotic stratum corneum (Munro microabscess). | *PMNs in parakeratotic stratum corneum (Munro microabscess). | ||
*Thinning of the suprapapillary plate. | *Thinning of the suprapapillary plate. | ||
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====Micro==== | ====Micro==== | ||
The sections show skin with | The sections show skin with regular psoriasiform change, hyperkeratosis, focal parakeratosis, prominent dilated vessels in the superficial dermis, superficial clusters of intraepidermal neutrophils (spongiform pustules) and thinning of the suprapapillary plate is present. A few perivascular inflammatory cells are present. | ||
dilated vessels in the superficial dermis, superficial clusters of intraepidermal | |||
neutrophils (spongiform pustules) and thinning of the suprapapillary plate is present. | |||
A few perivascular inflammatory cells are present. | |||
There is no epidermal necrosis. Eosinophils are not apparent. The lymphocytes do not have | There is no epidermal necrosis. Eosinophils are not apparent. The lymphocytes do not have significant atypia. | ||
significant atypia. | |||
==Lichen striatus== | ==Lichen striatus== | ||