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Difference between revisions of "In-transit metastasis"
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In-transit metastasis (view source)
Revision as of 13:39, 26 February 2016
, 13:39, 26 February 2016no edit summary
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==General== | ==General== | ||
*It is called "in-transit", as it happens while the tumour is on the way to the regional lymph node. | |||
*May be how a tumour (e.g. melanoma<ref name=pmid22329185>{{Cite journal | last1 = Grotz | first1 = TE. | last2 = Mansfield | first2 = AS. | last3 = Kottschade | first3 = LA. | last4 = Erickson | first4 = LA. | last5 = Otley | first5 = CC. | last6 = Markovic | first6 = SN. | last7 = Jakub | first7 = JW. | title = In-transit melanoma: an individualized approach. | journal = Oncology (Williston Park) | volume = 25 | issue = 14 | pages = 1340-8 | month = Dec | year = 2011 | doi = | PMID = 22329185 }}</ref><ref>{{Cite journal | last1 = Pawlik | first1 = TM. | last2 = Ross | first2 = MI. | last3 = Johnson | first3 = MM. | last4 = Schacherer | first4 = CW. | last5 = McClain | first5 = DM. | last6 = Mansfield | first6 = PF. | last7 = Lee | first7 = JE. | last8 = Cormier | first8 = JN. | last9 = Gershenwald | first9 = JE. | title = Predictors and natural history of in-transit melanoma after sentinel lymphadenectomy. | journal = Ann Surg Oncol | volume = 12 | issue = 8 | pages = 587-96 | month = Aug | year = 2005 | doi = 10.1245/ASO.2005.05.025 | PMID = 16021533 }}</ref>) recurs. | *May be how a tumour (e.g. melanoma<ref name=pmid22329185>{{Cite journal | last1 = Grotz | first1 = TE. | last2 = Mansfield | first2 = AS. | last3 = Kottschade | first3 = LA. | last4 = Erickson | first4 = LA. | last5 = Otley | first5 = CC. | last6 = Markovic | first6 = SN. | last7 = Jakub | first7 = JW. | title = In-transit melanoma: an individualized approach. | journal = Oncology (Williston Park) | volume = 25 | issue = 14 | pages = 1340-8 | month = Dec | year = 2011 | doi = | PMID = 22329185 }}</ref><ref>{{Cite journal | last1 = Pawlik | first1 = TM. | last2 = Ross | first2 = MI. | last3 = Johnson | first3 = MM. | last4 = Schacherer | first4 = CW. | last5 = McClain | first5 = DM. | last6 = Mansfield | first6 = PF. | last7 = Lee | first7 = JE. | last8 = Cormier | first8 = JN. | last9 = Gershenwald | first9 = JE. | title = Predictors and natural history of in-transit melanoma after sentinel lymphadenectomy. | journal = Ann Surg Oncol | volume = 12 | issue = 8 | pages = 587-96 | month = Aug | year = 2005 | doi = 10.1245/ASO.2005.05.025 | PMID = 16021533 }}</ref>) recurs. | ||
*Poor prognosticator. | *Poor prognosticator. | ||
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#Arises between the nearest (regional) [[lymph node]]s and the primary tumour. | #Arises between the nearest (regional) [[lymph node]]s and the primary tumour. | ||
#*The tumour presumably arises from a lymphatic that drains the tissue in which the primary tumour grew. | #*The tumour presumably arises from a lymphatic that drains the tissue in which the primary tumour grew. | ||
DDx: | DDx: | ||
*[[Satellitosis]] - | *[[Satellitosis]] - separate nodule <= 2 cm from the primary tumour. | ||
*[[Lymphovascular invasion]] - does not form a nodule and does not invade into the surround tissue. | *[[Lymphovascular invasion]] - does not form a nodule and does not invade into the surround tissue. | ||
*[[Lymph node metastasis]] - should have lymphoid tissue and capsule ''or'' be round; definitions dependent on the body site/primary tumour. | *[[Lymph node metastasis]] - should have lymphoid tissue and capsule ''or'' be round; definitions dependent on the body site/primary tumour. | ||