Difference between revisions of "Immunohistochemical staining"
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==Organ specific== | ==Organ specific== | ||
===Thyroid and lung=== | ===Thyroid and lung=== | ||
*TTF-1 ([[thyroid | *TTF-1 ([[thyroid transcription factor-1]]) -- +ve in thyroid gland malignancies. | ||
**Very good for [[breast]] vs. [[lung]].<ref name=pmid18318581>{{cite journal |author=Jagirdar J |title=Application of immunohistochemistry to the diagnosis of primary and metastatic carcinoma to the lung |journal=Arch. Pathol. Lab. Med. |volume=132 |issue=3 |pages=384–96 |year=2008 |month=March |pmid=18318581 |doi= |url=http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=132&page=384}}</ref> | **Very good for [[breast]] vs. [[lung]].<ref name=pmid18318581>{{cite journal |author=Jagirdar J |title=Application of immunohistochemistry to the diagnosis of primary and metastatic carcinoma to the lung |journal=Arch. Pathol. Lab. Med. |volume=132 |issue=3 |pages=384–96 |year=2008 |month=March |pmid=18318581 |doi= |url=http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=132&page=384}}</ref> | ||
***Often negative in squamous cell carcinoma of the lung (as with CK7 & CK20), though HMWK is usually positive. | ***Often negative in squamous cell carcinoma of the lung (as with CK7 & CK20), though HMWK is usually positive. | ||