Difference between revisions of "Immunohistochemical staining"

Immunohistochemical staining (view source)

632 bytes added , 15:31, 18 October 2011

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 *PSAP - prostatic specific acid phosphatase.
 *p63 - stains nuclei of basal cell in normal [[prostate]].
-*34betaE12 - stains basals cells in normal prostate.
+*34betaE12 - stains basal cells in normal prostate.
 *AMACR (racemase, P504S<ref>[http://www.antibodies-online.com/antibody/125649/P504S+alphaMethylacylCoA+Racemace+AMACR+Human/ http://www.antibodies-online.com/antibody/125649/P504S+alphaMethylacylCoA+Racemace+AMACR+Human/]</ref>) - present in adenocarcinoma (NOT in normal prostate).
-*CAP cocktail - AKA ''CAP'' (AMACR, p63 and 34βE12).
+*AR - usually present in prostate confined cancers.<ref name=pmid20878946>{{Cite journal  | last1 = Fleischmann | first1 = A. | last2 = Rocha | first2 = C. | last3 = Schobinger | first3 = S. | last4 = Seiler | first4 = R. | last5 = Wiese | first5 = B. | last6 = Thalmann | first6 = GN. | title = Androgen receptors are differentially expressed in Gleason patterns of prostate cancer and down-regulated in matched lymph node metastases. | journal = Prostate | volume = 71 | issue = 5 | pages = 453-60 | month = Apr | year = 2011 | doi = 10.1002/pros.21259 | PMID = 20878946 }}</ref>
+*CAP cocktail - [[AKA]] ''CAP'', [[AKA]] ''PIN-4'', [[AKA]] ''PIN''.
+**Consists of: AMACR, p63 and HMWK.
 **Image: [http://www.webpathology.com/image.asp?case=96&n=5 CAP cocktail (webpathology.com)].