Difference between revisions of "Immune thrombocytopenic purpura"

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==General==
==General==
*A common non-trauma reason for [[splenectomy]].<ref name=pmid24798604>{{Cite journal  | last1 = Jankulovski | first1 = N. | last2 = Antovic | first2 = S. | last3 = Kuzmanovska | first3 = B. | last4 = Mitevski | first4 = A. | title = Splenectomy for haematological disorders. | journal = Pril (Makedon Akad Nauk Umet Odd Med Nauki) | volume = 35 | issue = 1 | pages = 181-7 | month =  | year = 2014 | doi =  | PMID = 24798604 }}</ref>
*A common non-trauma reason for [[splenectomy]].<ref name=pmid24798604>{{Cite journal  | last1 = Jankulovski | first1 = N. | last2 = Antovic | first2 = S. | last3 = Kuzmanovska | first3 = B. | last4 = Mitevski | first4 = A. | title = Splenectomy for haematological disorders. | journal = Pril (Makedon Akad Nauk Umet Odd Med Nauki) | volume = 35 | issue = 1 | pages = 181-7 | month =  | year = 2014 | doi =  | PMID = 24798604 }}</ref>
*May be associated with [[Helicobacter pylori]] infections.<ref name=pmid25728540>{{Cite journal  | last1 = Frydman | first1 = GH. | last2 = Davis | first2 = N. | last3 = Beck | first3 = PL. | last4 = Fox | first4 = JG. | title = Helicobacter pylori Eradication in Patients with Immune Thrombocytopenic Purpura: A Review and the Role of Biogeography. | journal = Helicobacter | volume = 20 | issue = 4 | pages = 239-51 | month = Aug | year = 2015 | doi = 10.1111/hel.12200 | PMID = 25728540 }}</ref>
 
Presentation:
Presentation:
*Bleeding - usually.<ref name=pmid23714309>{{cite journal |author=Kistangari G, McCrae KR |title=Immune thrombocytopenia |journal=Hematol. Oncol. Clin. North Am. |volume=27 |issue=3 |pages=495–520 |year=2013 |month=June |pmid=23714309 |doi=10.1016/j.hoc.2013.03.001 |url=}}</ref>
*Bleeding - usually.<ref name=pmid23714309>{{cite journal |author=Kistangari G, McCrae KR |title=Immune thrombocytopenia |journal=Hematol. Oncol. Clin. North Am. |volume=27 |issue=3 |pages=495–520 |year=2013 |month=June |pmid=23714309 |doi=10.1016/j.hoc.2013.03.001 |url=}}</ref>
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***[[Systemic lupus erythematosus]].<ref>{{cite journal |author=Cines DB, Liebman H, Stasi R |title=Pathobiology of secondary immune thrombocytopenia |journal=Semin. Hematol. |volume=46 |issue=1 Suppl 2 |pages=S2–14 |year=2009 |month=January |pmid=19245930 |pmc=2682438 |doi=10.1053/j.seminhematol.2008.12.005 |url=}}</ref>
***[[Systemic lupus erythematosus]].<ref>{{cite journal |author=Cines DB, Liebman H, Stasi R |title=Pathobiology of secondary immune thrombocytopenia |journal=Semin. Hematol. |volume=46 |issue=1 Suppl 2 |pages=S2–14 |year=2009 |month=January |pmid=19245930 |pmc=2682438 |doi=10.1053/j.seminhematol.2008.12.005 |url=}}</ref>
**Viral.
**Viral.
**Bacterial - possibly [[Helicobacter pylori]].<ref>{{cite journal |author=Kuwana M |title=Helicobacter pylori-associated immune thrombocytopenia: clinical features and pathogenic mechanisms |journal=World J. Gastroenterol. |volume=20 |issue=3 |pages=714–23 |year=2014 |month=January |pmid=24574745 |pmc=3921481 |doi=10.3748/wjg.v20.i3.714 |url=}}</ref>
**Bacterial - possibly [[Helicobacter pylori]].<ref name=pmid24574745>{{cite journal |author=Kuwana M |title=Helicobacter pylori-associated immune thrombocytopenia: clinical features and pathogenic mechanisms |journal=World J. Gastroenterol. |volume=20 |issue=3 |pages=714–23 |year=2014 |month=January |pmid=24574745 |pmc=3921481 |doi=10.3748/wjg.v20.i3.714 |url=}}</ref><ref name=pmid25728540>{{Cite journal  | last1 = Frydman | first1 = GH. | last2 = Davis | first2 = N. | last3 = Beck | first3 = PL. | last4 = Fox | first4 = JG. | title = Helicobacter pylori Eradication in Patients with Immune Thrombocytopenic Purpura: A Review and the Role of Biogeography. | journal = Helicobacter | volume = 20 | issue = 4 | pages = 239-51 | month = Aug | year = 2015 | doi = 10.1111/hel.12200 | PMID = 25728540 }}</ref>


==Gross==
==Gross==
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     - Spleen with prominent red pulp macrophages and expanded germinal  
     - Spleen with prominent red pulp macrophages and expanded germinal  
       centres, pending hematopathology consult.
       centres, pending hematopathology consult.
</pre>
</pre>


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