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Difference between revisions of "IgG4-related systemic diseases"
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IgG4-related systemic diseases (view source)
Revision as of 14:45, 3 March 2022
, 14:45, 3 March 2022→Microscopic
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Features:<ref name=pmid28701054>{{cite journal |authors=Abraham M, Khosroshahi A |title=Diagnostic and treatment workup for IgG4-related disease |journal=Expert Rev Clin Immunol |volume=13 |issue=9 |pages=867–875 |date=September 2017 |pmid=28701054 |pmc=5896560 |doi=10.1080/1744666X.2017.1354698 |url=}}</ref> | Features:<ref name=pmid28701054>{{cite journal |authors=Abraham M, Khosroshahi A |title=Diagnostic and treatment workup for IgG4-related disease |journal=Expert Rev Clin Immunol |volume=13 |issue=9 |pages=867–875 |date=September 2017 |pmid=28701054 |pmc=5896560 |doi=10.1080/1744666X.2017.1354698 |url=}}</ref> | ||
*At least 10 IgG4 +ve plasma cells.† | *At least 10 IgG4 +ve plasma cells.† | ||
*>40% of plasma | *>40% of [[plasma cell]]s IgG4 +ve. | ||
Note: | Note: | ||
*† Minimum number dependent on anatomical site.<ref name=pmid28701054/> | *† Minimum number dependent on anatomical site.<ref name=pmid28701054/> | ||
** Lymph node: 100 (or 50) plasma cells/HPF, where 1 HPF ~ 0.196 mm*mm and 3 HPFs (0.588 mm*mm) are assessed.<ref>{{cite journal |authors=Cheuk W, Chan JK |title=Lymphadenopathy of IgG4-related disease: an underdiagnosed and overdiagnosed entity |journal=Semin Diagn Pathol |volume=29 |issue=4 |pages=226–34 |date=November 2012 |pmid=23068302 |doi=10.1053/j.semdp.2012.07.001 |url=}}</ref> | |||
==Sign-out== | |||
===Not present=== | |||
<pre> | |||
The provided clinical history is noted. Plasma cells are not readily apparent (<10 plasma cells/0.196 mm*mm). | |||
</pre> | |||
==See also== | |||
*[[Plasma cells]]. | |||
*[[HPFitis]]. | |||
==References== | ==References== | ||