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Difference between revisions of "Hypersensitivity"
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'''Hypersensitivity''' is a thingy one may get | '''Hypersensitivity''' is an inappropriate immune system response. It is a thingy one may get quizzed on. | ||
==Gell & Coombs classification== | |||
Gell & Coombs, in the 1960s, came-up with a classification that has endured. | |||
{|Class="wikitable" | {|Class="wikitable" | ||
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| '''Antibody mediated h.''' | | '''Antibody mediated h.''' | ||
| Cytotoxic antibody dependent h. | | Cytotoxic antibody dependent h. | ||
| [[Goodpasture syndrome]], [[Graves disease]] | | [[Goodpasture syndrome]],<ref name=pmid384140>{{Cite journal | last1 = Briggs | first1 = WA. | last2 = Johnson | first2 = JP. | last3 = Teichman | first3 = S. | last4 = Yeager | first4 = HC. | last5 = Wilson | first5 = CB. | title = Antiglomerular basement membrane antibody-mediated glomerulonephritis and Goodpasture's syndrome. | journal = Medicine (Baltimore) | volume = 58 | issue = 5 | pages = 348-61 | month = Sep | year = 1979 | doi = | PMID = 384140 }}</ref> [[Graves disease]] | ||
| antibodies (IgG, IgM) | | antibodies (IgG, IgM) | ||
| (antibody-mediated) phagocytosis & lysis | | (antibody-mediated) phagocytosis & lysis | ||
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| '''Cell-mediated h.''' | | '''Cell-mediated h.''' | ||
| Delayed-type hypersensitivity | | Delayed-type hypersensitivity | ||
| [[tuberculosis]], [[contact dermatitis]], chronic transplant rejection | | [[tuberculosis]], [[contact dermatitis]], chronic transplant rejection, [[inflammatory bowel disease]] | ||
| activated T cells | | activated T cells | ||
| perivascular inflammation, [[granuloma]]s | | perivascular inflammation, [[granuloma]]s | ||
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==See also== | ==See also== | ||
*[[Hypersensitivity pneumonitis]]. | *[[Hypersensitivity pneumonitis]]. | ||
*[[Common variable immunodeficiency]]. | |||
==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Stuff]] | [[Category:Stuff]] | ||