Difference between revisions of "Hodgkin lymphoma"

Hodgkin lymphoma (view source)

193 bytes added , 13:42, 13 August 2010

48,452

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 ==="UHN panel"===
-*CD45 -- +ve in NLPHL.
+{| class="wikitable"
-*CD20 -- +ve in NLPHL.
+|Antibody	|| NLPHL	|| CHL
-*BCL6.
+|-
-*MUM1<ref>URL: [http://www.ncbi.nlm.nih.gov/omim/601900 http://www.ncbi.nlm.nih.gov/omim/601900]. Accessed on: 10 August 2010.</ref> -- -ve in NLPHL.
+|CD45		|| +ve		|| -ve
-*CD30 -- +ve in CHL (most sensitive).
+|-
-*CD15 -- +ve in CHL.
+|CD20 		|| +ve 		|| -ve
-*CD21 -- +ve in HLPHL.
+|-
-*CD23.
+|BCL6		||		||
-*OCT-2 -- +ve NLPHL, -ve CHL.
+|-
-*PAX5 -- prove B cell linage in CHL.
+|MUM1<ref>URL: [http://www.ncbi.nlm.nih.gov/omim/601900 http://www.ncbi.nlm.nih.gov/omim/601900]. Accessed on: 10 August 2010.</ref> 	|| -ve 		||
+|-
-*CD3.
+|CD30 		|| -ve		|| +ve (most sensitive).
-*CD57 -- increased in NLPHL.
+|-
-*EBER.
+|CD15 		|| large cells -ve || +ve
-*EMA.
+|-
-*4 unstained.
+|CD21 		|| networks present	|| no networks
+|-
+|CD23 		|| networks present	|| no networks
+|-
+|OCT-2 		|| +ve 		|| -ve
+|-
+|PAX5 		||		|| prove B cell linage
+|-
+|CD3		||		||
+|-
+|CD57 		|| increased 	||
+|-
+|EBER		||		||
+|-
+|EMA		|| +/-		|| -ve
+|-
+|4 unstained 	||		||
+|}
 Notes:
 *NLPHL - usually surrounded by B cells.