Difference between revisions of "Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cell carcinoma"

Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cell carcinoma (view source)

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 ==Microscopic==
 Features - renal cell carcinoma:<ref name=pmid24441663>{{Cite journal  | last1 = Chen | first1 = YB. | last2 = Brannon | first2 = AR. | last3 = Toubaji | first3 = A. | last4 = Dudas | first4 = ME. | last5 = Won | first5 = HH. | last6 = Al-Ahmadie | first6 = HA. | last7 = Fine | first7 = SW. | last8 = Gopalan | first8 = A. | last9 = Frizzell | first9 = N. | title = Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cancer: recognition of the syndrome by pathologic features and the utility of detecting aberrant succination by immunohistochemistry. | journal = Am J Surg Pathol | volume = 38 | issue = 5 | pages = 627-37 | month = May | year = 2014 | doi = 10.1097/PAS.0000000000000163 | PMID = 24441663 }}</ref>
-*Large, (usually) eosinophilic, nucleolus with perinucleolar clearing - proposed hallmark - '''important'''.
+*Cells with:
-**May be focal.
+**Large, (usually) eosinophilic, nucleolus with perinucleolar clearing - proposed hallmark - '''important'''.
+***May be focal.
+**Abundant or moderate (eosinophilic) cytoplasm.
 *Variable architecture:
 **Papillary - classic description.