Difference between revisions of "Hereditary diffuse gastric cancer"

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'''Hereditary diffuse gastric cancer''', abbreviated '''HDGC''', is an important hereditary cause of diffuse [[gastric cancer]].<ref>{{cite journal |author=Sereno M, Aguayo C, Guillén Ponce C, ''et al.'' |title=Gastric tumours in hereditary cancer syndromes: clinical features, molecular biology and strategies for prevention |journal=Clin Transl Oncol |volume=13 |issue=9 |pages=599–610 |year=2011 |month=September |pmid=21865131 |doi= |url=}}</ref>
'''Hereditary diffuse gastric cancer''', abbreviated '''HDGC''', is an important hereditary cause of diffuse [[gastric cancer]].<ref>{{cite journal |author=Sereno M, Aguayo C, Guillén Ponce C, ''et al.'' |title=Gastric tumours in hereditary cancer syndromes: clinical features, molecular biology and strategies for prevention |journal=Clin Transl Oncol |volume=13 |issue=9 |pages=599–610 |year=2011 |month=September |pmid=21865131 |doi= |url=}}</ref>
It is caused by mutations in the epithelial cadherin gene (also ''E-cadherin'' and ''CDH1'').<ref name=omim137215>{{OMIM|137215}}</ref><Ref>{{OMIM|192090}}</ref>


==General==
==General==

Revision as of 00:34, 10 March 2014

Hereditary diffuse gastric cancer, abbreviated HDGC, is an important hereditary cause of diffuse gastric cancer.[1]

It is caused by mutations in the epithelial cadherin gene (also E-cadherin and CDH1).[2][3]

General

It is associated with:

See also

References

  1. Sereno M, Aguayo C, Guillén Ponce C, et al. (September 2011). "Gastric tumours in hereditary cancer syndromes: clinical features, molecular biology and strategies for prevention". Clin Transl Oncol 13 (9): 599–610. PMID 21865131.
  2. Online 'Mendelian Inheritance in Man' (OMIM) 137215
  3. Online 'Mendelian Inheritance in Man' (OMIM) 192090