Difference between revisions of "Hemorrhoid"

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#redirect [[Anus#hemorrhoids]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Hemorrhoid -- low mag.jpg
| Width      =
| Caption    = Hemorrhoid. [[H&E stain]].
| Micro      = polypoid lesion (epithelium on three sides) with large dilated veins and thick-walled vessels +/- fibrin thrombi, +/-edema, covered by squamous epithelium +/- keratinization and/or columnar epithelium
| Subtypes  =
| LMDDx      = [[fibroepithelial polyp]], vascular lesions (e.g. [[Kaposi sarcoma]])
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = [[rectum]]/[[anus]]
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      = +/-bright red blood per rectum
| Symptoms  = +/-itching, +/-pain
| Prevalence = very common
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    = other causes of rectal bleeding (e.g. [[colorectal carcinoma]]), [[malignant melanoma]]
}}
'''Hemorrhoid''' is a benign pathology of the rectal venous plexus, that may mimic more serious pathology, i.e. [[cancer]].
 
==General==
*Benign.
 
Clinical features:<ref>{{Cite journal  | last1 = Cazemier | first1 = M. | last2 = Felt-Bersma | first2 = RJ. | last3 = Cuesta | first3 = MA. | last4 = Mulder | first4 = CJ. | title = Elastic band ligation of hemorrhoids: flexible gastroscope or rigid proctoscope? | journal = World J Gastroenterol | volume = 13 | issue = 4 | pages = 585-7 | month = Jan | year = 2007 | doi =  | PMID = 17278225 }}</ref>
*[[Bright red blood per rectum]] (BRBPR).
*Pain.
*Itching.
*Prolapse.
 
==Gross==
Features:<ref name=Ref_GLP401>{{Ref GLP|401}}</ref>
*Grey mucosa.
*Pale or purple stroma.
 
DDx - clinical:
*[[Malignant melanoma]].<ref name=pmid11592745>{{Cite journal  | last1 = Felz | first1 = MW. | last2 = Winburn | first2 = GB. | last3 = Kallab | first3 = AM. | last4 = Lee | first4 = JR. | title = Anal melanoma: an aggressive malignancy masquerading as hemorrhoids. | journal = South Med J | volume = 94 | issue = 9 | pages = 880-5 | month = Sep | year = 2001 | doi =  | PMID = 11592745 }}
</ref>
 
==Microscopic==
Features:<ref name=Ref_GLP401>{{Ref GLP|401}}</ref>
*Polypoid lesion - epithelium on three sides:
**Large dilated veins and thick-walled vessels +/- fibrin thrombi - '''key feature'''.
**Edema.
**Squamous epithelium +/- keratinization ''or'' columnar epithelium.
 
DDx:
*[[Fibroepithelial polyp]].
*Vascular lesions.
**[[Kaposi sarcoma]].
**[[Angiosarcoma]].
**[[Arteriovenous malformation]] - has large arteries.
*[[Mucosal prolapse]].
 
===Image===
<gallery>
Image: Hemorrhoid -- very low mag.jpg | Hemorrhoid - very low mag. (WC)
Image: Hemorrhoid -- low mag.jpg | Hemorrhoid - low mag. (WC)
Image: Hemorrhoid - alt -- low mag.jpg | Hemorrhoid - low mag. (WC)
Image: Hemorrhoid -- intermed mag.jpg | Hemorrhoid - intermed. mag. (WC)
</gallery>
www:
*[http://www.profimedia.si/picture/longitudinal-section-of-human-rectum-hemorrhoid-tissue/0039860546/ Hemorrhoids (profimedia.si)].
 
==Sign out==
<pre>
ANAL LESION, REMOVAL:
- HEMORRHOID.
</pre>
 
<pre>
HEMORRHOIDS, EXCISION:
- HEMORRHOIDS.
</pre>
 
===Alternate===
<pre>
"EXTERNAL HEMORRHOID", EXCISION:
- POLYPOID FRAGMENTS OF RECTAL-TYPE MUCOSA WITH REACTIVE CHANGES, ULCERATION, SMOOTH
  MUSCLE HYPERPLASIA, AND GRANULATION TISSUE WITH INTERMEDIATE SIZE BLOOD VESSELS.
- NEGATIVE FOR DYSPLASIA.
</pre>
 
===Micro===
The sections show rectal and anal mucosa, and a submucosa with prominent blood vessels in a fibrotic stroma.  The rectal mucosa has focal reactive nuclear changes and evidence of prior erosions. The anal mucosa is unremarkable.
 
====Anal mucosa only====
The sections show anal mucosa, and submucosa with prominent blood vessels in a
fibrotic stroma. The anal mucosa is unremarkable.
 
==See also==
*[[Anus]].
*[[Colon]].
 
==References==
{{Reflist|2}}
 
[[Category:Anus]]
[[Category:Gastrointestinal pathology]]
[[Category:Diagnosis]]
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