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Difference between revisions of "Heart transplant pathology"
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Heart transplant pathology (view source)
Revision as of 21:14, 7 January 2011
, 21:14, 7 January 2011tweak
m (→Rejection) |
m (tweak) |
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| Line 9: | Line 9: | ||
| Image | | Image | ||
|- | |- | ||
| acute | | acute vascular | ||
| edema, dilated small vessels | | edema, dilated small vessels | ||
| scant inflammation | | scant inflammation | ||
| [http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig4 acute] | | [http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig4 acute] | ||
|- | |- | ||
| | | normal (0R) | ||
| normal | | normal | ||
| no extravascular monocytes | | no extravascular monocytes | ||
| | | | ||
|- | |- | ||
| cellular (1R) | | acute cellular (1R) | ||
| infiltrate, myocyte damage | | infiltrate, myocyte damage | ||
| scant interstitial infiltrate (lymphoplasmic), scant damage | | scant interstitial infiltrate (lymphoplasmic), scant damage | ||
| [http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig1 mild cellular] | | [http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig1 mild cellular] | ||
|- | |- | ||
| cellular (2R) | | acute cellular (2R) | ||
| space-occupying lesion | | space-occupying lesion | ||
| diffuse interstitial infiltrate displaces parenchyma (lymphoplasmic), obvious damage | | diffuse interstitial infiltrate displaces parenchyma (lymphoplasmic), obvious damage | ||
| [http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig2 mod. cellular], [http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig3 mod. cellular resolving] | | [http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig2 mod. cellular], [http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig3 mod. cellular resolving] | ||
|- | |- | ||
| cellular (3R) | | acute cellular (3R) | ||
| disruption of normal arch. | | disruption of normal arch. | ||
| diffuse interstitial infiltrate disrupts parenchyma (lymphoplasmic & PMNs), fibre loss/damage | | diffuse interstitial infiltrate disrupts parenchyma (lymphoplasmic & PMNs), fibre loss/damage | ||
| Line 118: | Line 118: | ||
*[http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig4 Acute rejection (pathconsultddx.com)]. | *[http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig4 Acute rejection (pathconsultddx.com)]. | ||
== | ==Acute cellular rejection== | ||
Grading scheme 2004/1990:<ref name=Ref_WMSP136>{{Ref WMSP|136}}</ref> | Grading scheme 2004/1990:<ref name=Ref_WMSP136>{{Ref WMSP|136}}</ref> | ||
{| class="wikitable" | {| class="wikitable" | ||