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Difference between revisions of "Hashimoto's thyroiditis"
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Hashimoto's thyroiditis (view source)
Revision as of 21:29, 13 September 2016
, 21:29, 13 September 2016→Clinical
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| Image = Hashimoto thyroiditis -- intermed mag.jpg | | Image = Hashimoto thyroiditis -- intermed mag.jpg | ||
| Width = | | Width = | ||
| Caption = Hashimoto thyroiditis. [[H&E stain]]. | | Caption = Lymphocytic thyroiditis with serologic evidence of Hashimoto's thyroiditis. [[H&E stain]]. | ||
| Synonyms = | | Synonyms = | ||
| Micro = polymorphous lymphoplasmacytic infiltrate with germinal centres, +/-nuclear clearing common, +/-oncocytic metaplasia | | Micro = polymorphous lymphoplasmacytic infiltrate with germinal centres, +/-nuclear clearing common, +/-oncocytic metaplasia | ||
| Line 51: | Line 51: | ||
**[[MALT lymphoma]]. | **[[MALT lymphoma]]. | ||
**[[Diffuse large B cell lymphoma]] (DLBCL). | **[[Diffuse large B cell lymphoma]] (DLBCL). | ||
===Hashimoto's thyroiditis and papillary thyroid carcinoma=== | |||
*Association between Hashimoto's and papillary thyroid carcinoma considered controversial - literature divided.<ref name=pmid25419066>{{Cite journal | last1 = Anand | first1 = A. | last2 = Singh | first2 = KR. | last3 = Kushwaha | first3 = JK. | last4 = Hussain | first4 = N. | last5 = Sonkar | first5 = AA. | title = Papillary Thyroid Cancer and Hashimoto's Thyroiditis: An Association Less Understood. | journal = Indian J Surg Oncol | volume = 5 | issue = 3 | pages = 199-204 | month = Sep | year = 2014 | doi = 10.1007/s13193-014-0325-4 | PMID = 25419066 }}</ref> | |||
**Jankovic ''et al.'' dispute that there is an association.<ref name=pmid23293329>{{Cite journal | last1 = Jankovic | first1 = B. | last2 = Le | first2 = KT. | last3 = Hershman | first3 = JM. | title = Clinical Review: Hashimoto's thyroiditis and papillary thyroid carcinoma: is there a correlation? | journal = J Clin Endocrinol Metab | volume = 98 | issue = 2 | pages = 474-82 | month = Feb | year = 2013 | doi = 10.1210/jc.2012-2978 | PMID = 23293329 }}</ref> | |||
**Zhang ''et al.'' show a correlation.<ref name=pmid24619663>{{Cite journal | last1 = Zhang | first1 = Y. | last2 = Dai | first2 = J. | last3 = Wu | first3 = T. | last4 = Yang | first4 = N. | last5 = Yin | first5 = Z. | title = The study of the coexistence of Hashimoto's thyroiditis with papillary thyroid carcinoma. | journal = J Cancer Res Clin Oncol | volume = 140 | issue = 6 | pages = 1021-6 | month = Jun | year = 2014 | doi = 10.1007/s00432-014-1629-z | PMID = 24619663 }}</ref> | |||
==Microscopic== | ==Microscopic== | ||
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*[[Diffuse large B cell lymphoma]]. | *[[Diffuse large B cell lymphoma]]. | ||
*[[Hürthle cell neoplasm]]. | *[[Hürthle cell neoplasm]]. | ||
===Images=== | |||
<gallery> | |||
Image: Hashimoto thyroiditis -- very low mag.jpg | HT - very low mag. (WC) | |||
Image: Hashimoto thyroiditis -- low mag.jpg | HT - low mag. (WC) | |||
Image: Hashimoto thyroiditis -- intermed mag.jpg | HT - intermed. mag. (WC) | |||
Image: Hashimoto thyroiditis -- high mag.jpg | HT - high mag. (WC) | |||
Image: Hashimoto thyroiditis - alt -- very low mag.jpg | HT - very low mag. (WC) | |||
Image: Hashimoto thyroiditis - alt -- intermed mag.jpg | HT - intermed. mag. (WC) | |||
</gallery> | |||
==IHC== | ==IHC== | ||
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==See also== | ==See also== | ||
*[[Thyroid gland]]. | *[[Thyroid gland]]. | ||
*[[Graves' disease]]. | |||
==References== | ==References== | ||