Difference between revisions of "Ground glass hepatocyte"

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The '''ground glass hepatocyte''' is a histologic finding that is seen in [[medical liver pathology]] and usually suggest a chronic [[hepatitis B]] infection.
[[Image:Ground glass hepatocytes high mag cropped 2.jpg|thumb|right|Ground glass hepatocytes. [[H&E stain]]. (WC)]]
The '''ground glass hepatocyte''', abbreviated '''GGH''', is a histologic finding that is seen in [[medical liver pathology]] and usually suggest a chronic [[hepatitis B]] infection.


==General==
==General==
*Usually suggests '''chronic''' [[HBV]] infection.
**Pattern NOT seen in acute HBV.
**Caused by virion particles.
===Classification===
===Classification===
*GGHs are not routinely classified.  
*GGHs are not routinely classified.  
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*Eosinophilic dull/hazy, somewhat irregular cytoplasm.
*Eosinophilic dull/hazy, somewhat irregular cytoplasm.
**Ground glass<ref>URL: [http://en.wikipedia.org/wiki/Ground_glass http://en.wikipedia.org/wiki/Ground_glass]. Accessed on: 7 June 2010.</ref> = glass with a rough/flat finish; glass that is translucent and has a matte finish.
**Ground glass<ref>URL: [http://en.wikipedia.org/wiki/Ground_glass http://en.wikipedia.org/wiki/Ground_glass]. Accessed on: 7 June 2010.</ref> = glass with a rough/flat finish; glass that is translucent and has a matte finish.
***The term is frequently used in radiology to describe hazy radiodense areas in the lung.<ref>URL: [http://www.healthsystem.virginia.edu/internet/radiology/educ/groundglass.cfm http://www.healthsystem.virginia.edu/internet/radiology/educ/groundglass.cfm]. Accessed on: 7 June 2010.</ref>
***The term is frequently used in radiology to describe hazy radiodense areas in the [[lung]].<ref>URL: [http://www.healthsystem.virginia.edu/internet/radiology/educ/groundglass.cfm http://www.healthsystem.virginia.edu/internet/radiology/educ/groundglass.cfm]. Accessed on: 7 June 2010.</ref>
*Usually suggests '''chronic''' [[HBV]] infection.
**Pattern NOT seen in acute HBV.
**Caused by virion particles.


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===Images===
===Images===
<gallery>
<gallery>
Image:Ground_glass_hepatocytes_high_mag_cropped_2.jpg | Ground glass hepatocytes. (WC/Nephron)
Image:Ground glass hepatocytes intermed mag 2.jpg | GGH - intermed. mag. (WC)
Image:Ground_glass_hepatocytes_high_mag_cropped.jpg | Ground glass hepatocyte. (WC/Nephron)
Image:Ground glass hepatocytes high mag 2.jpg | GGH - high mag. (WC)
Image:Ground_glass_hepatocytes_high_mag_cropped_2.jpg | GGH - high mag. (cropped) (WC)
Image:Ground_glass_hepatocytes_high_mag_cropped.jpg | GGH - high mag. (cropped) (WC)
</gallery>
</gallery>
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