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Difference between revisions of "Granulomatosis with polyangiitis"
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Granulomatosis with polyangiitis (view source)
Revision as of 22:01, 28 November 2016
, 22:01, 28 November 2016no edit summary
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Wegener's granulomatosis -b- high mag.jpg | |||
| Width = | |||
| Caption = Granulomatosis with polyangiitis. [[H&E stain]]. | |||
| Synonyms = Wegener's granulomatosis (old term) | |||
| Micro = | |||
| Subtypes = | |||
| LMDDx = small vessel vasculitis (inflammatory cells within the vessel wall, vessel wall injury - such as fibrinoid necrosis), granulomas - typically poorly formed | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Staging = | |||
| Site = [[blood vessels]] - see ''[[vasculitides]]'' | |||
| Assdx = renal failure (due to [[rapidly progressive glomerulonephritis]]), [[pulmonary hemorrhage]] | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = epistasis | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = PR3-ANCA (c-ANCA) +ve | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = dependent on presentation - nasal lesion: cocaine use; other causes of [[pulmonary hemorrhage]]; other causes of [[rapidly progressive glomerulonephritis]] | |||
| Tx = | |||
}} | |||
'''Granulomatosis with polyangiitis''', abbreviated '''GPA''', is a type of [[vasculitis]] that typically afflicts the [[lung]]s and [[kidney]]s. | '''Granulomatosis with polyangiitis''', abbreviated '''GPA''', is a type of [[vasculitis]] that typically afflicts the [[lung]]s and [[kidney]]s. | ||
It was previously known as '''Wegener granulomatosis''', abbreviated '''WG'''. | It was previously known as '''Wegener's granulomatosis''', abbreviated '''WG'''. | ||
It should '''''not''''' be confused with ''[[eosinophilic granulomatosis with polyangiitis]]'', previously known as ''Churg-Strauss syndrome''. | It should '''''not''''' be confused with ''[[eosinophilic granulomatosis with polyangiitis]]'', previously known as ''Churg-Strauss syndrome''. | ||