Granulation tissue

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Granulation tissue forms when wound heal.

Gross

  • Looks granular, ergo the name granulation tissue.

Image:

Microscopic

Features:

  • Blood vessel rich - key element.[1]
    • Small size ~ ~25 micrometers in diameter. (???)
  • Proliferation of fibroblasts - key element.
  • Inflammation (esp. lymphocytes).

Images:

References

  1. Howdieshell TR, Callaway D, Webb WL, et al. (April 2001). "Antibody neutralization of vascular endothelial growth factor inhibits wound granulation tissue formation". J. Surg. Res. 96 (2): 173–82. doi:10.1006/jsre.2001.6089. PMID 11266270.
  2. URL: http://www.siumed.edu/~dking2/intro/inflskin.htm. Accessed on: 17 January 2011.