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''Sinonasal hemangiopericytoma'' may be abbreviated ''SNHPC''.<ref name=pmid22430770/> | ''Sinonasal hemangiopericytoma'' may be abbreviated ''SNHPC''.<ref name=pmid22430770/> | ||
==General== | |||
*May be associated with ''[[oncogenic osteomalacia]]''.<ref name=pmid22430770/> | |||
*Thought to arise from the pericytes.<ref name=pmid22801124>{{Cite journal | last1 = Arpaci | first1 = RB. | last2 = Kara | first2 = T. | last3 = Vayisoğlu | first3 = Y. | last4 = Ozgur | first4 = A. | last5 = Ozcan | first5 = C. | title = Sinonasal glomangiopericytoma. | journal = J Craniofac Surg | volume = 23 | issue = 4 | pages = 1194-6 | month = Jul | year = 2012 | doi = 10.1097/SCS.0b013e31824e6d09 | PMID = 22801124 }}</ref> | |||
*Rare <1% of sinonasal tumours.<ref name=pmid22801124/> | |||
==Microscopic== | ==Microscopic== | ||
Features:<ref name=pmid22430770/> | Features:<ref name=pmid22430770/> | ||
* | *Short spindle cells/epithelioid cells with: | ||
**Bland round/oval nuclei with fine chromatin. | **Bland round/oval nuclei with fine chromatin. | ||
**Scant cytoplasm. | **Scant cytoplasm. | ||
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DDx: | DDx: | ||
*[[Phosphaturic mesenchymal tumour, mixed connective tissue type]] - grungy calcs, acellular matrix deposition. | *[[Phosphaturic mesenchymal tumour, mixed connective tissue type]] - grungy calcs, acellular matrix deposition. | ||
*Other [[small round cell tumours]]. | |||
*[[Biphenotypic sinonasal sarcoma]] - head and neck lesion. | |||
===Images=== | ===Images=== | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311951/figure/Fig1/ SNHPC - low mag. (nih.gov)].<ref name=pmid22430770/> | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311951/figure/Fig1/ SNHPC - low mag. (nih.gov)].<ref name=pmid22430770/> | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311951/figure/Fig3/ SNHPC - high mag. (nih.gov)].<ref name=pmid22430770>{{Cite journal | last1 = Brandwein-Gensler | first1 = M. | last2 = Siegal | first2 = GP. | title = Striking pathology gold: a singular experience with daily reverberations: sinonasal hemangiopericytoma (glomangiopericytoma) and oncogenic osteomalacia. | journal = Head Neck Pathol | volume = 6 | issue = 1 | pages = 64-74 | month = Mar | year = 2012 | doi = 10.1007/s12105-012-0337-8 | PMID = 22430770 }}</ref> | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311951/figure/Fig3/ SNHPC - high mag. (nih.gov)].<ref name=pmid22430770>{{Cite journal | last1 = Brandwein-Gensler | first1 = M. | last2 = Siegal | first2 = GP. | title = Striking pathology gold: a singular experience with daily reverberations: sinonasal hemangiopericytoma (glomangiopericytoma) and oncogenic osteomalacia. | journal = Head Neck Pathol | volume = 6 | issue = 1 | pages = 64-74 | month = Mar | year = 2012 | doi = 10.1007/s12105-012-0337-8 | PMID = 22430770 }}</ref> | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851559/figure/F3/ SNHPC (nih.gov)].<ref name=pmid24074285/> | |||
==IHC== | |||
Features:<ref name=pmid24074285>{{Cite journal | last1 = Sun | first1 = Q. | last2 = Zhang | first2 = C. | last3 = Chen | first3 = W. | last4 = He | first4 = Y. | title = The molecular mechanisms on glomangiopericytoma invasion. | journal = Orphanet J Rare Dis | volume = 8 | issue = | pages = 152 | month = | year = 2013 | doi = 10.1186/1750-1172-8-152 | PMID = 24074285 }}</ref> | |||
*Vimentin +ve. | |||
*SMA +ve. | |||
*MSA +ve. | |||
*CD31 -ve. | |||
*CD34 -ve. | |||
==See also== | ==See also== | ||
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==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Weird stuff]] |
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