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Difference between revisions of "Glassy cell carcinoma"
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = Glassy_cell_carcinoma_- | | Image = Glassy_cell_carcinoma_-_very_high_mag.jpg | ||
| Width = | | Width = | ||
| Caption = Glassy cell carcinoma. [[H&E stain]]. | | Caption = Glassy cell carcinoma. [[H&E stain]]. | ||
| Line 7: | Line 7: | ||
| Micro = epithelioid cells in sheets or cords with a round/oval nucleus, one or more prominent nucleoli, abundant finely vacuolated eosinophilic to amphophilic cytoplasm, distinct cell borders, inflammation - especially eosinophils | | Micro = epithelioid cells in sheets or cords with a round/oval nucleus, one or more prominent nucleoli, abundant finely vacuolated eosinophilic to amphophilic cytoplasm, distinct cell borders, inflammation - especially eosinophils | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[ | | LMDDx = [[adenosquamous carcinoma of the uterine cervix]], [[squamous carcinoma of the uterine cervix]] | ||
| Stains = [[PAS stain]] +ve (plasma membrane) | | Stains = [[PAS stain]] +ve (plasma membrane) | ||
| IHC = | | IHC = | ||
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'''Glassy cell carcinoma''', abbreviated '''GCC''', is a rare [[malignancy]] of the [[uterine cervix]]. | '''Glassy cell carcinoma''', abbreviated '''GCC''', is a rare [[malignancy]] of the [[uterine cervix]]. | ||
It is considered to be a subtype of [[adenosquamous carcinoma of the uterine cervix]]. | |||
==General== | ==General== | ||
*Rare. | *Rare. | ||
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**Round/oval nucleus. | **Round/oval nucleus. | ||
**One or more prominent nucleoli. | **One or more prominent nucleoli. | ||
**Abundant finely vacuolated eosinophilic to amphophilic cytoplasm. | **Abundant finely vacuolated eosinophilic to amphophilic cytoplasm - looks "glassy". | ||
**Distinct cell borders. | **Distinct cell borders. | ||
*Inflammation - esp. eosinophils.<ref>URL: [http://www.webpathology.com/image.asp?n=2&Case=561 http://www.webpathology.com/image.asp?n=2&Case=561]. Accessed on: 4 September 2011.</ref> | *Inflammation - esp. eosinophils.<ref>URL: [http://www.webpathology.com/image.asp?n=2&Case=561 http://www.webpathology.com/image.asp?n=2&Case=561]. Accessed on: 4 September 2011.</ref> | ||