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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Gastric_antral_vascular_ectasia_-_very_high_mag.jpg | |||
| Width = | |||
| Caption = Gastric antral vascular ectasia. [[H&E stain]]. | |||
| Micro = fibrin thrombi (characteristic feature), dilated capillaries in lamina propria, +/-foveollar hyperplasia | |||
| Subtypes = | |||
| LMDDx = [[portal hypertensive gastropathy]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[stomach]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = 60s or 70s, females:males >2:1 | |||
| Signs = +/- melena | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = usu. [[anemia]] | |||
| Rads = | |||
| Endoscopy = linear red streaks in antrum - watermelon-like | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = | |||
}} | |||
{{ Infobox external links | |||
| Name = {{PAGENAME}} | |||
| EHVSC = | |||
| EHVSC_mult = | |||
| pathprotocols = | |||
| wikipedia = gastric antral vascular ectasia | |||
| pathoutlines = | |||
}} | |||
'''Gastric antral vascular ectasia''', abbreviated '''GAVE''', is an uncommon pathology of the [[stomach]]. It is also known as '''watermelon stomach''' due to characteristic endoscopic appearance.<ref name=pmid18625989>{{cite journal |author=Chatterjee S |title=Watermelon stomach |journal=CMAJ |volume=179 |issue=2 |pages=162 |year=2008 |month=July |pmid=18625989 |pmc=2443230 |doi=10.1503/cmaj.080461 |url=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=18625989}}</ref> | '''Gastric antral vascular ectasia''', abbreviated '''GAVE''', is an uncommon pathology of the [[stomach]]. It is also known as '''watermelon stomach''' due to characteristic endoscopic appearance.<ref name=pmid18625989>{{cite journal |author=Chatterjee S |title=Watermelon stomach |journal=CMAJ |volume=179 |issue=2 |pages=162 |year=2008 |month=July |pmid=18625989 |pmc=2443230 |doi=10.1503/cmaj.080461 |url=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=18625989}}</ref> | ||
==General== | ==General== | ||
* | *Etiology not well understood.<ref name=pmid20011731/> | ||
*Typically presents with gastrointestinal bleeding or [[anemia]]. | |||
*Age - usually 60s or 70s. | |||
*Females:males >2:1.<ref name=pmid20011731>{{Cite journal | last1 = Rosenfeld | first1 = G. | last2 = Enns | first2 = R. | title = Argon photocoagulation in the treatment of gastric antral vascular ectasia and radiation proctitis. | journal = Can J Gastroenterol | volume = 23 | issue = 12 | pages = 801-4 | month = Dec | year = 2009 | doi = | PMID = 20011731 | PMC = 2805515 }}</ref> | |||
==Gross/endoscopic appearance== | ==Gross/endoscopic appearance== | ||
* Linear red streaks in antrum - oriented toward the pyloric valve... vaguely resembles a watermelon. | * Linear red streaks in antrum - streaks oriented toward the pyloric valve... vaguely resembles a watermelon. | ||
Endoscopic images: | ===Endoscopic images=== | ||
<gallery> | |||
Image:Gastric antral vascular ectasia (before and after).png |GAVE - before and after treatment. (WC) | |||
</gallery> | |||
www: | |||
*[http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2443230&rendertype=figure&id=f1-19 Watermelon stomach (pubmedcentral.nih.gov)]. | *[http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2443230&rendertype=figure&id=f1-19 Watermelon stomach (pubmedcentral.nih.gov)]. | ||
==Microscopic== | ==Microscopic== | ||
Features:<ref name=Ref_GLP118>{{Ref GLP|118}}</ref> | Features:<ref name=Ref_GLP118>{{Ref GLP|118}}</ref> | ||
*Fibrin thrombi - '''characteristic feature'''. | *Fibrin thrombi - '''characteristic feature'''. | ||
*Dilated capillaries in lamina propria. | *Dilated capillaries in lamina propria - '''important feature'''. | ||
*+/-Foveollar hyperplasia.<ref name=Ref_GLP119>{{Ref GLP|119}}</ref> | *+/-Foveollar hyperplasia.<ref name=Ref_GLP119>{{Ref GLP|119}}</ref> | ||
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Image:Gastric_antral_vascular_ectasia_-_2_-_intermed_mag.jpg | GAVE - intermed. mag. (WC) | Image:Gastric_antral_vascular_ectasia_-_2_-_intermed_mag.jpg | GAVE - intermed. mag. (WC) | ||
Image:Gastric_antral_vascular_ectasia_-_2_-_very_high_mag.jpg | GAVE - very high mag. (WC) | Image:Gastric_antral_vascular_ectasia_-_2_-_very_high_mag.jpg | GAVE - very high mag. (WC) | ||
</gallery> | |||
<gallery> | |||
Image:Gastric antral vascular ectasia - low mag.jpg | GAVE - low mag. (WC) | |||
Image:Gastric antral vascular ectasia - intermed mag.jpg | GAVE - intermed. mag. (WC) | |||
Image:Gastric antral vascular ectasia - high mag.jpg | GAVE - high mag. (WC) | |||
Image:Gastric_antral_vascular_ectasia_-_very_high_mag.jpg | GAVE - two thrombi - very high mag. (WC) | Image:Gastric_antral_vascular_ectasia_-_very_high_mag.jpg | GAVE - two thrombi - very high mag. (WC) | ||
</gallery> | </gallery> |
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