Difference between revisions of "Gastric antral vascular ectasia"

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#redirect [[Stomach#Gastric_antral_vascular_ectasia]]
'''Gastric antral vascular ectasia''', abbreviated '''GAVE''', is an uncommon pathology of the [[stomach]]. It is also known as '''watermelon stomach''' due to characteristic endoscopic appearance.<ref name=pmid18625989>{{cite journal |author=Chatterjee S |title=Watermelon stomach |journal=CMAJ |volume=179 |issue=2 |pages=162 |year=2008 |month=July |pmid=18625989 |pmc=2443230 |doi=10.1503/cmaj.080461 |url=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=18625989}}</ref>
 
==General==
*Lesion of the antrum - due to dilated capillaries.
 
==Gross/endoscopic appearance==
* Linear red streaks in antrum - oriented toward the pyloric valve... vaguely resembles a watermelon.
 
Endoscopic images:
*[http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2443230&rendertype=figure&id=f1-19 Watermelon stomach (pubmedcentral.nih.gov)].
*[http://en.wikipedia.org/wiki/File:Gave.png GAVE (WP)].
 
==Microscopic==
Features:<ref name=Ref_GLP118>{{Ref GLP|118}}</ref>
*Fibrin thrombi - '''characteristic feature'''.
*Dilated capillaries in lamina propria.
*+/-Foveollar hyperplasia.<ref name=Ref_GLP119>{{Ref GLP|119}}</ref>
 
DDx:
*[[Portal hypertensive gastropathy]] - predominantly in the gastric body, usu. associated with [[cirrhosis]], do not have fibrin thrombi.<ref name=Ref_GLP120-1>{{Ref GLP|120-1}}</ref>
 
===Images===
<gallery>
Image:Gastric_antral_vascular_ectasia_-_2_-_intermed_mag.jpg | GAVE - intermed. mag. (WC)
Image:Gastric_antral_vascular_ectasia_-_2_-_very_high_mag.jpg | GAVE - very high mag. (WC)
Image:Gastric_antral_vascular_ectasia_-_very_high_mag.jpg | GAVE - two thrombi - very high mag. (WC)
</gallery>
 
==Sign out==
<pre>
STOMACH, BIOPSY:
- GASTRIC ANTRAL VASCULAR ECTASIA WITH FOVEOLAR HYPERPLASIA.
- MILD CHRONIC ACTIVE ANTRAL GASTRITIS.
- NEGATIVE FOR INTESTINAL METAPLASIA.
- NEGATIVE FOR DYSPLASIA.
- NEGATIVE FOR HELICOBACTER ORGANISMS.
</pre>
 
===Micro===
The sections show antral-type gastric mucosa with dilated lamina propria blood vessels and intravascular fibrin thrombi. There is mild foveolar hyperplasia. Numerous neutrophils are present between the foveollar cells and within the lamina propria.  Several large clusters of plasma cells are present in the lamina propria.
 
==See also==
*[[Stomach]].
 
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Stomach]]
[[Category:Gastrointestinal pathology]]

Revision as of 15:13, 15 August 2013

Gastric antral vascular ectasia, abbreviated GAVE, is an uncommon pathology of the stomach. It is also known as watermelon stomach due to characteristic endoscopic appearance.[1]

General

  • Lesion of the antrum - due to dilated capillaries.

Gross/endoscopic appearance

  • Linear red streaks in antrum - oriented toward the pyloric valve... vaguely resembles a watermelon.

Endoscopic images:

Microscopic

Features:[2]

  • Fibrin thrombi - characteristic feature.
  • Dilated capillaries in lamina propria.
  • +/-Foveollar hyperplasia.[3]

DDx:

Images

Sign out

STOMACH, BIOPSY: 
- GASTRIC ANTRAL VASCULAR ECTASIA WITH FOVEOLAR HYPERPLASIA.
- MILD CHRONIC ACTIVE ANTRAL GASTRITIS.
- NEGATIVE FOR INTESTINAL METAPLASIA. 
- NEGATIVE FOR DYSPLASIA. 
- NEGATIVE FOR HELICOBACTER ORGANISMS.

Micro

The sections show antral-type gastric mucosa with dilated lamina propria blood vessels and intravascular fibrin thrombi. There is mild foveolar hyperplasia. Numerous neutrophils are present between the foveollar cells and within the lamina propria. Several large clusters of plasma cells are present in the lamina propria.

See also

References

  1. Chatterjee S (July 2008). "Watermelon stomach". CMAJ 179 (2): 162. doi:10.1503/cmaj.080461. PMC 2443230. PMID 18625989. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=18625989.
  2. Iacobuzio-Donahue, Christine A.; Montgomery, Elizabeth A. (2005). Gastrointestinal and Liver Pathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 118. ISBN 978-0443066573.
  3. Iacobuzio-Donahue, Christine A.; Montgomery, Elizabeth A. (2005). Gastrointestinal and Liver Pathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 119. ISBN 978-0443066573.
  4. Iacobuzio-Donahue, Christine A.; Montgomery, Elizabeth A. (2005). Gastrointestinal and Liver Pathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 120-1. ISBN 978-0443066573.