GATA3

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GATA3 an immunostain that is increasingly used in genitourinary pathology.

GATA3
Immunostain in short

GATA3 staining in benign urothelium.
Use bladder versus prostate, bladder versus SCC
Subspeciality Genitourinary pathology
Normal staining pattern nuclear
Positive urothelial carcinoma, lobular breast carcinoma
Negative prostatic carcinoma, squamous cell carcinoma of the lung

Positive

Images

Negative

See also

References

  1. 1.0 1.1 1.2 Chang A, Amin A, Gabrielson E, et al. (October 2012). "Utility of GATA3 immunohistochemistry in differentiating urothelial carcinoma from prostate adenocarcinoma and squamous cell carcinomas of the uterine cervix, anus, and lung". Am. J. Surg. Pathol. 36 (10): 1472–6. doi:10.1097/PAS.0b013e318260cde7. PMC 3444740. PMID 22982890. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444740/. Cite error: Invalid <ref> tag; name "pmid22982890" defined multiple times with different content Cite error: Invalid <ref> tag; name "pmid22982890" defined multiple times with different content
  2. Ellis, CL.; Chang, AG.; Cimino-Mathews, A.; Argani, P.; Youssef, RF.; Kapur, P.; Montgomery, EA.; Epstein, JI. (Nov 2013). "GATA-3 immunohistochemistry in the differential diagnosis of adenocarcinoma of the urinary bladder.". Am J Surg Pathol 37 (11): 1756-60. doi:10.1097/PAS.0b013e31829cdba7. PMID 24061521.