Fuchs dystrophy

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Fuchs dystrophy, also Fuchs endothelial dystrophy, is a rare pathology of the eye that may be seen in Descemet's membrane specimens.

General

  • Uncommon.

Microscopic

Features:[1]

  • Guttae accumulations.
    • Collagenous material from the basement membrane.
  • Decreased endothelial density.[2]
  • Thickening of Descemet's membrane.[3]

Images

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Decemet's Membrane, Right Eye, Excision:
- Loss of endothelial cells and guttata formation compatible with Fuch's dystrophy.

See also

References

  1. McLaren, JW.; Bachman, LA.; Kane, KM.; Patel, SV. (Feb 2014). "Objective assessment of the corneal endothelium in Fuchs' endothelial dystrophy.". Invest Ophthalmol Vis Sci 55 (2): 1184-90. doi:10.1167/iovs.13-13041. PMID 24508788.
  2. 2.0 2.1 Klintworth, GK. (2009). "Corneal dystrophies.". Orphanet J Rare Dis 4: 7. doi:10.1186/1750-1172-4-7. PMID 19236704.
  3. URL: http://www.mrcophth.com/pathology/fuchendothelialdystrophy.html. Accessed on: 27 August 2015.