Difference between revisions of "Fuchs dystrophy"

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'''Fuchs dystrophy''', also '''Fuchs endothelial dystrophy''', is a rare pathology of the [[eye]] that may be seen in ''Descemet's membrane'' specimens.
'''Fuchs dystrophy''', also '''Fuchs endothelial dystrophy''', is a rare pathology of the [[eye]] that may be seen in ''[[Descemet's membrane]]'' specimens.


==General==
==General==

Latest revision as of 14:12, 13 October 2015

Fuchs dystrophy, also Fuchs endothelial dystrophy, is a rare pathology of the eye that may be seen in Descemet's membrane specimens.

General

  • Uncommon.

Microscopic

Features:[1]

  • Gutta.
    • Accumulation of collagenous material from the basement membrane.
  • Decreased endothelial density.[2]
  • Thickening of Descemet's membrane.[3]
    • Older normal individuals: 16 +/- 2 micrometres.[4]
    • Fuchs dystrophy: 34 +/- 11 micrometres.[4]

Images

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Descemet’s Membrane, Right Eye, Excision:
- Thickened Descemet’s membrane with marked decrease of endothelial cells and gutta consistent with Fuch's dystrophy.

See also

References

  1. McLaren, JW.; Bachman, LA.; Kane, KM.; Patel, SV. (Feb 2014). "Objective assessment of the corneal endothelium in Fuchs' endothelial dystrophy.". Invest Ophthalmol Vis Sci 55 (2): 1184-90. doi:10.1167/iovs.13-13041. PMID 24508788.
  2. 2.0 2.1 Klintworth, GK. (2009). "Corneal dystrophies.". Orphanet J Rare Dis 4: 7. doi:10.1186/1750-1172-4-7. PMID 19236704.
  3. URL: http://www.mrcophth.com/pathology/fuchendothelialdystrophy.html. Accessed on: 27 August 2015.
  4. 4.0 4.1 Shousha, MA.; Perez, VL.; Wang, J.; Ide, T.; Jiao, S.; Chen, Q.; Chang, V.; Buchser, N. et al. (Jun 2010). "Use of ultra-high-resolution optical coherence tomography to detect in vivo characteristics of Descemet's membrane in Fuchs' dystrophy.". Ophthalmology 117 (6): 1220-7. doi:10.1016/j.ophtha.2009.10.027. PMID 20163865.