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Difference between revisions of "Fuchs dystrophy"
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'''Fuchs | '''Fuchs dystrophy''', also '''Fuchs endothelial dystrophy''', is a rare pathology of the [[eye]] that may be seen in ''[[Descemet's membrane]]'' specimens. | ||
==General== | ==General== | ||
| Line 6: | Line 6: | ||
==Microscopic== | ==Microscopic== | ||
Features:<ref name=pmid24508788>{{Cite journal | last1 = McLaren | first1 = JW. | last2 = Bachman | first2 = LA. | last3 = Kane | first3 = KM. | last4 = Patel | first4 = SV. | title = Objective assessment of the corneal endothelium in Fuchs' endothelial dystrophy. | journal = Invest Ophthalmol Vis Sci | volume = 55 | issue = 2 | pages = 1184-90 | month = Feb | year = 2014 | doi = 10.1167/iovs.13-13041 | PMID = 24508788 }}</ref> | Features:<ref name=pmid24508788>{{Cite journal | last1 = McLaren | first1 = JW. | last2 = Bachman | first2 = LA. | last3 = Kane | first3 = KM. | last4 = Patel | first4 = SV. | title = Objective assessment of the corneal endothelium in Fuchs' endothelial dystrophy. | journal = Invest Ophthalmol Vis Sci | volume = 55 | issue = 2 | pages = 1184-90 | month = Feb | year = 2014 | doi = 10.1167/iovs.13-13041 | PMID = 24508788 }}</ref> | ||
* | *Gutta. | ||
** | **Accumulation of collagenous material from the basement membrane. | ||
*Decreased endothelial density. | *Decreased endothelial density.<ref name=pmid19236704>{{Cite journal | last1 = Klintworth | first1 = GK. | title = Corneal dystrophies. | journal = Orphanet J Rare Dis | volume = 4 | issue = | pages = 7 | month = | year = 2009 | doi = 10.1186/1750-1172-4-7 | PMID = 19236704 }}</ref> | ||
*Thickening of ''Descemet's membrane''.<ref>URL: [http://www.mrcophth.com/pathology/fuchendothelialdystrophy.html http://www.mrcophth.com/pathology/fuchendothelialdystrophy.html]. Accessed on: 27 August 2015.</ref> | |||
**Older normal individuals: 16 +/- 2 micrometres.<ref name=pmid20163865/> | |||
**Fuchs dystrophy: 34 +/- 11 micrometres.<ref name=pmid20163865>{{Cite journal | last1 = Shousha | first1 = MA. | last2 = Perez | first2 = VL. | last3 = Wang | first3 = J. | last4 = Ide | first4 = T. | last5 = Jiao | first5 = S. | last6 = Chen | first6 = Q. | last7 = Chang | first7 = V. | last8 = Buchser | first8 = N. | last9 = Dubovy | first9 = SR. | title = Use of ultra-high-resolution optical coherence tomography to detect in vivo characteristics of Descemet's membrane in Fuchs' dystrophy. | journal = Ophthalmology | volume = 117 | issue = 6 | pages = 1220-7 | month = Jun | year = 2010 | doi = 10.1016/j.ophtha.2009.10.027 | PMID = 20163865 }}</ref> | |||
===Images=== | |||
<gallery> | |||
Image:Fuchs dystrophy 1.JPG |Fuchs dystrophy. (WC) | |||
</gallery> | |||
www: | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695576/figure/F56/ Fuchs dystrophy (nlm.nih.gov)].<ref name=pmid19236704/> | |||
==Sign out== | |||
<pre> | |||
Descemet’s Membrane, Right Eye, Excision: | |||
- Thickened Descemet’s membrane with marked decrease of endothelial cells and gutta consistent with Fuch's dystrophy. | |||
</pre> | |||
==See also== | ==See also== | ||
*[[Eye]]. | *[[Eye]]. | ||
*[[Pseudophakic bullous keratopathy]]. | |||
==References== | ==References== | ||