Difference between revisions of "Fibrous dysplasia"

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Image:Fibrous_dysplasia_-_intermed_mag.jpg | Fibrous dysplasia - intermed. mag. (WC/Nephron)
Image:Fibrous_dysplasia_-_intermed_mag.jpg | Fibrous dysplasia - intermed. mag. (WC/Nephron)
Image:Fibrous_dysplasia_-_high_mag.jpg | Fibrous dysplasia - high mag. (WC/Nephron)
Image:Fibrous_dysplasia_-_high_mag.jpg | Fibrous dysplasia - high mag. (WC/Nephron)
Image:File:Bone FibrousDysplasia LP CTR.jpg|thumb|Medium power shot with the classic 'Chinese character' bone spicules.
Image:Bone FibrousDysplasia LP CTR.jpg|thumb|Medium power shot with the classic 'Chinese character' bone spicules.
Image:File:Bone FibrousDysplasia Jaw MP3 PA.JPG|thumb|Immature bony trabeculae in a fibrous stroma.
Image:Bone FibrousDysplasia Jaw MP3 PA.JPG|thumb|Immature bony trabeculae in a fibrous stroma.
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Revision as of 05:18, 19 October 2014

Fibrous dysplasia
Diagnosis in short

Fibrous dysplasia. H&E stain.

Synonyms osteitis fibrosa

LM woven bone with odd irregular shapes (often described as "chinese characters"), fibrous tissue around bone, no osteoblastic rimming
LM DDx desmoplastic fibroma, low-grade fibrosarcoma, low-grade central osteosarcoma
Site bone

Syndromes McCune-Albright syndrome

Prevalence uncommon
Prognosis benign

Fibrous dysplasia, also osteitis fibrosa, is a rare disorder of bone that has a distinctive microscopic appearance.

General

Classification:

  • Monostotic - one bone involved, ~80% of cases.
  • Polyostotic - several bones involved, ~20% of cases.

Microscopic

Features:[1]

  • Woven bone with odd irregular shapes - key feature.
    • Described as "chinese characters".[2]
  • Fibrous tissue around bone.

Notes:

  • No osteoblastic rimming.

DDx:

Images

www:

See also

References