Difference between revisions of "Fibromatoses"
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*[[Desmoid-type fibromatosis]]. | *[[Desmoid-type fibromatosis]]. | ||
*Others. | *Others. | ||
==Gross== | |||
*Firm. | |||
*Infiltrative borders. | |||
Image: | |||
*[http://www.flickr.com/photos/kcrazypathgirl/5858963062/ Desmoid tumour (flickr.com)]. | |||
*[http://www.flickr.com/photos/lunarcaustic/5334047938/ Mesenteric fibromatosis (flickr.com)]. | |||
==Microscopic== | ==Microscopic== | ||
| Line 27: | Line 35: | ||
*[[Nodular fasciitis]]. | *[[Nodular fasciitis]]. | ||
*[[Dermatofibroma]]. | *[[Dermatofibroma]]. | ||
*[[GIST]]. | |||
Image: | Image: | ||
*[http://www.sarcomaimages.com/index.php?v=Plantar-Fibromatosis Plantar fibromatosis (sarcomaimages.com)]. | *[http://www.sarcomaimages.com/index.php?v=Plantar-Fibromatosis Plantar fibromatosis (sarcomaimages.com)]. | ||
*[http://www.flickr.com/photos/lunarcaustic/5333412517/in/photostream/ Mesenteric fibromatosis (flickr.com)]. | |||
==IHC== | |||
*Beta-catenin +ve.{{fact}} | |||
*CD117 -ve. | |||
==See also== | ==See also== | ||
Revision as of 13:46, 18 September 2012
Fibromatoses are a group of benign stromal lesions that may be seen in pediatric pathology and may or may not be associated with syndromes.
Syndromes associated with fibromatoses
- Familial adenomatous polyposis.[1]
- Hereditary desmoid syndrome.
Types
Superficial
- Palmar (Dupuytren's contracture).
- Plantar.
- Penile (Peyronie's disease).
Deep
- Desmoid-type fibromatosis.
- Others.
Gross
- Firm.
- Infiltrative borders.
Image:
Microscopic
Features:
- Bland spindle cells - typically in fascicles.
- Small thin blood vessels that are parallel to one another.
- Nuclei of blood vessels are typically darker staining than those of the lesion.
DDx:
- Metaplastic carcinoma, e.g. metaplastic breast carcinoma.
- Nodular fasciitis.
- Dermatofibroma.
- GIST.
Image:
IHC
- Beta-catenin +ve.[citation needed]
- CD117 -ve.
See also
References
- ↑ Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; Aster, Jon (2009). Robbins and Cotran pathologic basis of disease (8th ed.). Elsevier Saunders. pp. 1092. ISBN 978-1416031215.