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Fibroepithelial polyp (view source)
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'''Fibroepithelial polyp''', also known as '''acrochordon''' and '''skin tag''', is a very common benign skin lesion. | '''Fibroepithelial polyp''', also known as '''acrochordon''' and '''skin tag''', is a very common benign skin lesion. | ||
The lesion in the mouth is dealt with in the article ''[[oral fibroma]]''. | |||
==General== | ==General== | ||
*Benign. | *Benign. | ||
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*May be associated with pregnancy, [[diabetes]], [[intestinal polyposis]].<ref name=Ref_PCPBoD8|596>{{Ref PCPBoD8|596}}</ref> | *May be associated with pregnancy, [[diabetes]], [[intestinal polyposis]].<ref name=Ref_PCPBoD8|596>{{Ref PCPBoD8|596}}</ref> | ||
*Can be a component of ''[[Birt–Hogg–Dubé syndrome]]''. | *Can be a component of ''[[Birt–Hogg–Dubé syndrome]]''. | ||
May be divided into: | |||
*Epithelial type - abundant epithelium. | |||
*Stromal type - abundant fibrous stroma. | |||
==Gross== | ==Gross== | ||
*Raised skin-coloured lesion. | *Raised skin-coloured lesion. | ||
DDx - clinical: | |||
* | *Skin tag-like nevus. | ||
===Image=== | |||
<gallery> | |||
Image:Skintagblemish.jpg | Skin tag. (WC) | |||
</gallery> | |||
==Microscopic== | ==Microscopic== | ||
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*[[Nevus lipomatosus superficialis]] - abundant adipocytes in the superficial dermis. | *[[Nevus lipomatosus superficialis]] - abundant adipocytes in the superficial dermis. | ||
*[[Neurofibroma]]. | *[[Neurofibroma]]. | ||
*[[Seborrheic keratosis]] - usu. horn cysts. | |||
===Images=== | ===Images=== | ||
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*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20080802171929218 Fibroepithelial polyp (surgicalpathologyatlas.com)]. | *[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20080802171929218 Fibroepithelial polyp (surgicalpathologyatlas.com)]. | ||
*[http://dermatology-s10.cdlib.org/143/case_presentations/skintags/3.jpg Inflamed fibroepithelial polyp (cdlib.org)].<ref>URL: [http://dermatology-s10.cdlib.org/143/case_presentations/skintags/allegue.html http://dermatology-s10.cdlib.org/143/case_presentations/skintags/allegue.html]. Accessed on: 9 January 2013.</ref> | *[http://dermatology-s10.cdlib.org/143/case_presentations/skintags/3.jpg Inflamed fibroepithelial polyp (cdlib.org)].<ref>URL: [http://dermatology-s10.cdlib.org/143/case_presentations/skintags/allegue.html http://dermatology-s10.cdlib.org/143/case_presentations/skintags/allegue.html]. Accessed on: 9 January 2013.</ref> | ||
==Sign out== | ==Sign out== | ||
<pre> | <pre> | ||
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===Micro=== | ===Micro=== | ||
The sections show a fragment of skin with epithelium on three sides. The epithelium matures normally and is not hypertrophic. Orthokeratosis is present. The core of the lesion has fibrous tissue. There is no significant inflammation. No melanocytic nests are identified. | The sections show a fragment of skin with epithelium on three sides. The epithelium matures normally and is not hypertrophic. Orthokeratosis is present. The core of the lesion has fibrous tissue. There is no significant inflammation. No melanocytic nests are identified. | ||
====Hyperkeratosis==== | |||
The sections show a fragment of skin with epithelium on three sides. The epidermis matures | |||
toward the surface and no significant basilar atypia is identified. A prominent granular layer is present. Mild hyperkeratosis is present. The core of the lesion consists of fibrous tissue. There is no significant inflammation. No | |||
melanocytic nests are identified. | |||
====Inflamed==== | ====Inflamed==== | ||
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There is mild basal nuclear enlargement. No significant nuclear atypia is apparent. The | There is mild basal nuclear enlargement. No significant nuclear atypia is apparent. The | ||
dermal-epidermal interface is well-demarcated. Rare basal mitotic activity is identified. | dermal-epidermal interface is well-demarcated. Rare basal mitotic activity is identified. | ||
====Epithelial-type==== | |||
The sections show skin with epithelium on three sides, acanthosis and hyperkeratosis. No pseudohorn cysts are identified. A granular layer is present. Mild basal | |||
nuclear atypia is present. Mitotic activity is present but basal. Minimal parakeratosis is | |||
present. No melanocytic nests are identified. No solar elastosis is apparent in the limited | |||
dermis. No koilocytes are apparent. | |||
==See also== | ==See also== | ||
*[[Non-malignant skin disease]]. | *[[Non-malignant skin disease]]. | ||
*[[Eyelid]]. | |||
==References== | ==References== | ||