Difference between revisions of "Fibroblast growth factor receptors"

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'''Fibroblast growth factor receptor''', abbreviated '''FGFR''', a molecule that transmit growth signals for fibroblasts.
'''Fibroblast growth factor receptor''', abbreviated '''FGFR''', a molecule that transmit growth signals for fibroblasts.
''FGFR2'' and ''FGFR3'' redirect here.


An anti-FGFR therapy exists (''erdafitinib'').<ref>{{cite journal |vauthors=Sheth H, Limaye S, Kumar P, Shreenivas A |title=Sustained response on sequential anti-FGFR therapy in metastatic gall bladder cancer: a case report and literature review |journal=J Cancer Res Clin Oncol |volume=149 |issue=8 |pages=4915–4923 |date=July 2023 |pmid=36307559 |doi=10.1007/s00432-022-04428-w |url=}}</ref><ref>{{cite journal |vauthors=Al-Obaidy KI, Cheng L |title=Fibroblast growth factor receptor (FGFR) gene: pathogenesis and treatment implications in urothelial carcinoma of the bladder |journal=J Clin Pathol |volume=74 |issue=8 |pages=491–495 |date=August 2021 |pmid=33731335 |doi=10.1136/jclinpath-2020-207115 |url=}}</ref>
An anti-FGFR therapy exists (''erdafitinib'').<ref>{{cite journal |vauthors=Sheth H, Limaye S, Kumar P, Shreenivas A |title=Sustained response on sequential anti-FGFR therapy in metastatic gall bladder cancer: a case report and literature review |journal=J Cancer Res Clin Oncol |volume=149 |issue=8 |pages=4915–4923 |date=July 2023 |pmid=36307559 |doi=10.1007/s00432-022-04428-w |url=}}</ref><ref name=pmid33731335>{{cite journal |vauthors=Al-Obaidy KI, Cheng L |title=Fibroblast growth factor receptor (FGFR) gene: pathogenesis and treatment implications in urothelial carcinoma of the bladder |journal=J Clin Pathol |volume=74 |issue=8 |pages=491–495 |date=August 2021 |pmid=33731335 |doi=10.1136/jclinpath-2020-207115 |url=}}</ref>
 
==Anti-FGFR therapy==
It is used in:
*[[Urothelial carcinoma]].<ref name=pmid33731335/>
*Hepatobiliary cancers.{{fact}}
 
==See also==
*[[Classification of urothelial carcinoma by immunohistochemistry]].


==References==
==References==
{{Reflist|1}}
{{Reflist|1}}


[[Category:Molecular Pathology]]
[[Category:Molecular pathology]]

Latest revision as of 16:23, 8 March 2024

Fibroblast growth factor receptor, abbreviated FGFR, a molecule that transmit growth signals for fibroblasts. FGFR2 and FGFR3 redirect here.

An anti-FGFR therapy exists (erdafitinib).[1][2]

Anti-FGFR therapy

It is used in:

See also

References

  1. "Sustained response on sequential anti-FGFR therapy in metastatic gall bladder cancer: a case report and literature review". J Cancer Res Clin Oncol 149 (8): 4915–4923. July 2023. doi:10.1007/s00432-022-04428-w. PMID 36307559.
  2. 2.0 2.1 "Fibroblast growth factor receptor (FGFR) gene: pathogenesis and treatment implications in urothelial carcinoma of the bladder". J Clin Pathol 74 (8): 491–495. August 2021. doi:10.1136/jclinpath-2020-207115. PMID 33731335.