Extrarenal malignant rhabdoid tumour

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Extrarenal malignant rhabdoid tumour is a rare malignant tumour typically seen in children.

It is essentially identical to the renal malignant rhabdoid tumour.[1]

General

Microscopic

Features:[1]

  • Variable architecture.
  • Round cells.
  • Eccentric vesicular nucleus.
  • Prominent nucleolus -- key feature.

DDx:

IHC

Others:[5]

  • Vimentin +ve.
  • EMA +ve.
  • AE1/AE3 +ve.
  • CAM5.2 +ve.

See also

References

  1. 1.0 1.1 1.2 Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 627. ISBN 978-0781765275.
  2. Uwineza, A.; Gill, H.; Buckley, P.; Owens, C.; Capra, M.; O'Sullivan, C.; McDermott, M.; Brett, F. et al. (Sep 2014). "Rhabdoid tumor: the Irish experience 1986-2013.". Cancer Genet 207 (9): 398-402. doi:10.1016/j.cancergen.2014.05.015. PMID 25085603.
  3. Liang, L.; Tatevian, N.; Bhattacharjee, M.; Tsao, K.; Hicks, J. (Aug 2014). "Desmoplastic small round cell tumor with atypical immunohistochemical profile and rhabdoid-like differentiation.". World J Clin Cases 2 (8): 367-72. doi:10.12998/wjcc.v2.i8.367. PMID 25133149.
  4. Ishida, M.; Iwai, M.; Yoshida, K.; Kagotani, A.; Okabe, H. (2014). "Rhabdoid melanoma: a case report with review of the literature.". Int J Clin Exp Pathol 7 (2): 840-3. PMID 24551314.
  5. Wang, H.; Ma, Y.; Li, J.; Zhang, D.; Wu, B.; Fang, C.; Chen, L. (Dec 2014). "[Extrarenal malignant rhabdoid tumor of childhood: a clinicopathologic analysis of 8 cases].". Zhonghua Bing Li Xue Za Zhi 43 (12): 805-8. PMID 25623976.