Eosinophilic granulomatosis with polyangiitis

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Eosinophilic granulomatosis with polyangiitis, previously known as Churg-Strauss syndrome,[1] is a type of vasculitis.

Eosinophilic granulomatosis with polyangiitis
Diagnosis in short

Eosinophilic granulomatosis with polyangiitis. H&E stain.

LM small vessel vasculitis with abundant eosinophils and granulomas
LM DDx eosinophilic vasculitis associated with a connective tissue disease
Site blood vessels

Associated Dx asthma
Signs fever
Prevalence rare

General

Defining features - memory device GAFE:

  • Granulomata.
  • Asthma.
  • Fever.
  • Eosinophilia.

Notes:

Microscopic

Features:

DDx:

Images

See also

References

  1. Stone, JR.; Bruneval, P.; Angelini, A.; Bartoloni, G.; Basso, C.; Batoroeva, L.; Buja, LM.; Butany, J. et al. "Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases.". Cardiovasc Pathol 24 (5): 267-78. doi:10.1016/j.carpath.2015.05.001. PMID 26051917.
  2. URL: http://emedicine.medscape.com/article/334024-overview. Accessed on: 22 January 2011.
  3. Chen, KR.; Su, WP.; Pittelkow, MR.; Conn, DL.; George, T.; Leiferman, KM. (Aug 1996). "Eosinophilic vasculitis in connective tissue disease.". J Am Acad Dermatol 35 (2 Pt 1): 173-82. PMID 8708015.