Difference between revisions of "Eosinophilic cholecystitis"

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{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Eosinophilic cholecystitis -- low mag.jpg
| Width      =
| Caption    = Eosinophilic cholecystitis. [[H&E stain]]. (WC)
| Synonyms  =
| Micro      = gallbladder wall with inflammatory infiltrate that is >90% [[eosinophil]]s
| Subtypes  = (subtype of acute cholecystitis)
| LMDDx      = [[acute cholecystitis]] with eosinophils
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Staging    =
| Site      = [[gallbladder]]
| Assdx      = eosinophilic cholangitis, hypereosinophilic syndromes, parasitic infection
| Syndromes  =
| Clinicalhx =
| Signs      = see ''[[acute cholecystitis]]''
| Symptoms  =
| Prevalence = rare - case reports
| Bloodwork  = +/-eosinophilia
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    = [[acute cholecystitis]]
| Tx        = cholecystectomy
}}
'''Eosinophilic cholecystitis''' is a rare type of [[cholecystitis]].
'''Eosinophilic cholecystitis''' is a rare type of [[cholecystitis]].


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*Eosinophilic cholangitis.
*Eosinophilic cholangitis.
*Hypereosinophilic syndromes (HES).
*Hypereosinophilic syndromes (HES).
*Parasitic infestations.
*Parasitic infection.


==Microscopic==
==Microscopic==
Features:
Features:
*Gallbladder wall with inflammtory infiltrate that is >90% eosinophils.<ref name=pmid17522376>{{Cite journal  | last1 = Shakov | first1 = R. | last2 = Simoni | first2 = G. | last3 = Villacin | first3 = A. | last4 = Baddoura | first4 = W. | title = Eosinophilic cholecystitis, with a review of the literature. | journal = Ann Clin Lab Sci | volume = 37 | issue = 2 | pages = 182-5 | month =  | year = 2007 | doi =  | PMID = 17522376 }}</ref><ref name=pmid24638193>{{Cite journal  | last1 = Choudhury | first1 = M. | last2 = Pujani | first2 = M. | last3 = Katiyar | first3 = Y. | last4 = Jyotsna | first4 = PL. | last5 = Rautela | first5 = A. | title = Idiopathic eosinophilic cholecystitis with cholelithiasis: a report of two cases. | journal = Turk Patoloji Derg | volume = 30 | issue = 2 | pages = 142-4 | month =  | year = 2014 | doi = 10.5146/tjpath.2014.01235 | PMID = 24638193 }}</ref>
*Gallbladder wall with inflammatory infiltrate that is >90% eosinophils.<ref name=pmid17522376>{{Cite journal  | last1 = Shakov | first1 = R. | last2 = Simoni | first2 = G. | last3 = Villacin | first3 = A. | last4 = Baddoura | first4 = W. | title = Eosinophilic cholecystitis, with a review of the literature. | journal = Ann Clin Lab Sci | volume = 37 | issue = 2 | pages = 182-5 | month =  | year = 2007 | doi =  | PMID = 17522376 }}</ref><ref name=pmid24638193>{{Cite journal  | last1 = Choudhury | first1 = M. | last2 = Pujani | first2 = M. | last3 = Katiyar | first3 = Y. | last4 = Jyotsna | first4 = PL. | last5 = Rautela | first5 = A. | title = Idiopathic eosinophilic cholecystitis with cholelithiasis: a report of two cases. | journal = Turk Patoloji Derg | volume = 30 | issue = 2 | pages = 142-4 | month =  | year = 2014 | doi = 10.5146/tjpath.2014.01235 | PMID = 24638193 }}</ref>


DDx:
DDx:
*[[Acute cholecystitis]].
*[[Acute cholecystitis]].
===Images===
<gallery>
Image: Eosinophilic cholecystitis -- extremely low mag.jpg | EC - extremely low mag. (WC)
Image: Eosinophilic cholecystitis -- very low mag.jpg | EC - very low mag. (WC)
Image: Eosinophilic cholecystitis -- low mag.jpg | EC - low mag. (WC)
Image: Eosinophilic cholecystitis -- intermed mag.jpg | EC - intermed. mag. (WC)
Image: Eosinophilic cholecystitis -- high mag.jpg | EC - high mag. (WC)
Image: Eosinophilic cholecystitis - alt -- very low mag.jpg | EC - very low mag. (WC)
Image: Eosinophilic cholecystitis - alt -- low mag.jpg | EC - low mag. (WC)
</gallery>
==Sign out==
<pre>
Gallbladder, Cholecystectomy:
- Eosinophilic cholecystitis and cholelithiasis, see comment.
Comment:
Eosinophilic cholecystitis may be idiopathic or associated with other conditions characterized by eosinophilia, including but not limited to parasitic infections and hypereosinophilic syndromes. Clinical correlation is required.
</pre>
===Verbose===
<pre>
Gallbladder, Cholecystectomy:
    - Eosinophilic cholecystitis and cholelithiasis, see comment.
Comment:
The histopathologic diagnosis of eosinophilic cholecystitis is in keeping with the clinical impression of acute cholecystitis.
Eosinophilic cholecystitis may be idiopathic or associated with other conditions characterized by eosinophilia, including but not limited to parasitic infections and hypereosinophilic syndromes. Clinical correlation is required.
</pre>


==See also==
==See also==
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