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[[Image:Eosinophilic_colitis_--_very_high_mag.jpg|thumb|right|350px|Eosinophils in [[eosinophilic colitis]]. [[H&E stain]].]] | |||
'''Eosinophil''' is a common type of white blood cell. | '''Eosinophil''' is a common type of white blood cell. | ||
== | ==General== | ||
===Diseases with many eosinophils=== | |||
*Infection - esp. [[fungus|fungal]]. | *Infection - esp. [[fungus|fungal]]. | ||
*[[Drug reaction]]. | *[[Drug reaction]]. | ||
*[[Inflammatory fibroid polyp]]. | *[[Inflammatory fibroid polyp]]. | ||
*[[ | *[[Eosinophilic granulomatosis with polyangiitis]] (Churg-Strauss syndrome). | ||
*[[ | *[[Asthma]]. | ||
*[[Kimura disease]]. | |||
*[[Inflammatory bowel disease]]. | |||
*[[Langerhans cell histiocytosis]]. | *[[Langerhans cell histiocytosis]]. | ||
*[[ | *Hypereosinophilic syndrome (HES).<ref>{{Cite journal | last1 = Podjasek | first1 = JC. | last2 = Butterfield | first2 = JH. | title = Mortality in hypereosinophilic syndrome: 19 years of experience at Mayo Clinic with a review of the literature. | journal = Leuk Res | volume = 37 | issue = 4 | pages = 392-5 | month = Apr | year = 2013 | doi = 10.1016/j.leukres.2012.12.016 | PMID = 23332454 }}</ref> | ||
====Neoplastic related==== | |||
*Eosinophilic myeloproliferative neoplasm.<ref>{{Cite journal | last1 = Noel | first1 = P. | last2 = Mesa | first2 = RA. | title = Eosinophilic myeloid neoplasms. | journal = Curr Opin Hematol | volume = 20 | issue = 2 | pages = 157-62 | month = Mar | year = 2013 | doi = 10.1097/MOH.0b013e32835d81bf | PMID = 23385615 }}</ref> | |||
*[[Hodgkin lymphoma]] - eosinophils not malignant. | |||
===Site specific=== | ====Site specific==== | ||
*[[Eosinophilic esophagitis]]. | *[[Eosinophilic esophagitis]]. | ||
*[[Eosinophilic colitis]]. | *[[Eosinophilic colitis]]. | ||
*[[Eosinophilic gastritis]]. | |||
*[[Eosinophilic cholecystitis]]. | |||
*[[Pulmonary Langerhans cell histiocytosis]]. | *[[Pulmonary Langerhans cell histiocytosis]]. | ||
*[[Angiolymphoid hyperplasia with eosinophilia]] (ALHE) - skin. | *[[Angiolymphoid hyperplasia with eosinophilia]] (ALHE) - skin. | ||
==Microscopic== | |||
Features: | |||
*Bilobed nucleus. | |||
*Granular eosinophilic cytoplasm. | |||
DDx: | |||
*[[Paneth cell]]s - for intraepithelial eosinophils. | |||
**Eosinophils have smaller (~1/2) more intensely red granules. | |||
===Images=== | |||
<gallery> | |||
Image:Eosinophilic colitis - alt -- very high mag.jpg | Eosinophils in [[eosinophilic colitis]]. (WC) | |||
</gallery> | |||
==See also== | ==See also== | ||
*[[Neutrophil]]. | *[[Neutrophil]]. | ||
==References== | |||
{{Reflist|2}} | |||
[[Category:Basics]] | [[Category:Basics]] | ||