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Difference between revisions of "Endometritis"
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→Acute endometritis
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Endometritis_-_2_-_cropped_-_very_high_mag.jpg | |||
| Width = | |||
| Caption = Chronic endometritis. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = ''acute'': abundant [[neutrophils]], clusters >5 (in stroma & glands);<br> ''chronic'': plasma cells (key feature), often eosinophils, lymphoid aggregates | |||
| Subtypes = acute, chronic | |||
| LMDDx = [[menstrual endometrium]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[endometrium]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = +/-postpartum, +/-recent instrumentation | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Endometritis''' is inflammation of the [[endometrium]]. It usually subdivided into ''acute'' and ''chronic''. | '''Endometritis''' is inflammation of the [[endometrium]]. It usually subdivided into ''acute'' and ''chronic''. | ||
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==Microscopic== | ==Microscopic== | ||
===Acute endometritis=== | ===Acute endometritis=== | ||
Features: | Features:{{fact}} | ||
*Neutrophils clusters (>5 | *Neutrophils clusters (>5 [[PMN]]s) in the: | ||
**Endometrial stroma. | **Endometrial stroma. | ||
**Within uterine glands. | **Within uterine glands. | ||
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*Neutrophils are normal in the context of menses. | *Neutrophils are normal in the context of menses. | ||
Image | DDx: | ||
*[[Menstrual endometrium]] - less neutrophils. (???) | |||
====Kiviat definition==== | |||
Kiviat ''et al.'' definition - requires both:<ref name=pmid2137304>{{cite journal |author=Kiviat NB, Wølner-Hanssen P, Eschenbach DA, ''et al.'' |title=Endometrial histopathology in patients with culture-proved upper genital tract infection and laparoscopically diagnosed acute salpingitis |journal=Am. J. Surg. Pathol. |volume=14 |issue=2 |pages=167–75 |year=1990 |month=February |pmid=2137304 |doi= |url=}}</ref> | |||
#>=5 [[PMN]]s in surface epithelium/400x magnification field of view. | |||
#>=1 [[plasma cell]] in the endometrial stroma/120x magnification field of view. | |||
Notes: | |||
*Above definition is considered "widely accepted".<ref name=pmid>{{cite journal |author=Ross JD |title=What is endometritis and does it require treatment? |journal=Sex Transm Infect |volume=80 |issue=4 |pages=252–3 |year=2004 |month=August |pmid=15295119 |pmc=1744883 |doi=10.1136/sti.2004.009548 |url=}}</ref> | |||
*Definition suffers from [[HPFitis]] and [[IPFitis]]. | |||
====Image==== | |||
*[http://www.hsc.stonybrook.edu/gyn-atlas/UT53.10.1.htm Acute endometritis (stonybrook.edu)]. | *[http://www.hsc.stonybrook.edu/gyn-atlas/UT53.10.1.htm Acute endometritis (stonybrook.edu)]. | ||
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Notes: | Notes: | ||
*One [[plasma cell]] is not enough to call it. | *One [[plasma cell]] is not enough to call it.<ref name=pmid21996319>{{cite journal |author=Vicetti Miguel RD, Chivukula M, Krishnamurti U, ''et al.'' |title=Limitations of the criteria used to diagnose histologic endometritis in epidemiologic pelvic inflammatory disease research |journal=Pathol. Res. Pract. |volume=207 |issue=11 |pages=680–5 |year=2011 |month=November |pmid=21996319 |pmc=3215901 |doi=10.1016/j.prp.2011.08.007 |url=}}</ref><ref name=pmid16873562>{{Cite journal | last1 = McCluggage | first1 = WG. | title = My approach to the interpretation of endometrial biopsies and curettings. | journal = J Clin Pathol | volume = 59 | issue = 8 | pages = 801-12 | month = Aug | year = 2006 | doi = 10.1136/jcp.2005.029702 | PMID = 16873562 }}</ref> | ||
DDx: | DDx: | ||
* | *[[Menstrual endometrium]] - endometrial stromal condensation. | ||
===Images=== | ===Images=== | ||