Difference between revisions of "End-stage kidney"
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End- | '''End-stage kidney''' is a non-functional [[kidney]]. | ||
==General== | |||
*Many end-stage renal disease (ESRD) kidneys have a similar appearance. | *Many end-stage renal disease (ESRD) kidneys have a similar appearance. | ||
**Notable exception: polycystic kidney diseases have distinctive appearance, e.g. [[ADPKD]]. | **Notable exception: polycystic kidney diseases have distinctive appearance, e.g. [[ADPKD]]. | ||
==Gross== | |||
*Small kidneys. | *Small kidneys. | ||
*Thinned renal cortex. | *Thinned renal cortex. | ||
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*Normal (adult) kidneys are ~11 cm from pole-to-pole.<ref name=pmid20030823>{{Cite journal | last1 = Glodny | first1 = B. | last2 = Unterholzner | first2 = V. | last3 = Taferner | first3 = B. | last4 = Hofmann | first4 = KJ. | last5 = Rehder | first5 = P. | last6 = Strasak | first6 = A. | last7 = Petersen | first7 = J. | title = Normal kidney size and its influencing factors - a 64-slice MDCT study of 1.040 asymptomatic patients. | journal = BMC Urol | volume = 9 | issue = | pages = 19 | month = | year = 2009 | doi = 10.1186/1471-2490-9-19 | PMID = 20030823 | URL = http://www.biomedcentral.com/1471-2490/9/19 }}</ref> | *Normal (adult) kidneys are ~11 cm from pole-to-pole.<ref name=pmid20030823>{{Cite journal | last1 = Glodny | first1 = B. | last2 = Unterholzner | first2 = V. | last3 = Taferner | first3 = B. | last4 = Hofmann | first4 = KJ. | last5 = Rehder | first5 = P. | last6 = Strasak | first6 = A. | last7 = Petersen | first7 = J. | title = Normal kidney size and its influencing factors - a 64-slice MDCT study of 1.040 asymptomatic patients. | journal = BMC Urol | volume = 9 | issue = | pages = 19 | month = | year = 2009 | doi = 10.1186/1471-2490-9-19 | PMID = 20030823 | URL = http://www.biomedcentral.com/1471-2490/9/19 }}</ref> | ||
==Microscopic== | |||
Features: | Features: | ||
*Global sclerosis of the glomeruli. | *Global sclerosis of the glomeruli. | ||
Revision as of 00:16, 12 January 2014
End-stage kidney is a non-functional kidney.
General
- Many end-stage renal disease (ESRD) kidneys have a similar appearance.
- Notable exception: polycystic kidney diseases have distinctive appearance, e.g. ADPKD.
Gross
- Small kidneys.
- Thinned renal cortex.
- +/-Dilated renal calyces.
- +/-Cysts.
Note:
- Normal (adult) kidneys are ~11 cm from pole-to-pole.[1]
Microscopic
Features:
- Global sclerosis of the glomeruli.
- Interstitial fibrosis.
- +/-Thyroidization - colloid-like hyaline cast formation that impart an appearance that mimics the thyroid gland:[2]
- Typical of chronic pyelonephritis and obstructive nephropathy.
Image:
See also
References
- ↑ Glodny, B.; Unterholzner, V.; Taferner, B.; Hofmann, KJ.; Rehder, P.; Strasak, A.; Petersen, J. (2009). "Normal kidney size and its influencing factors - a 64-slice MDCT study of 1.040 asymptomatic patients.". BMC Urol 9: 19. doi:10.1186/1471-2490-9-19. PMID 20030823.
- ↑ Ito, S.; Kobayashi, A.; Tsuchiya, T.; Moriyama, Y.; Kikuchi, M.; Deguchi, T.; Yamaguchi, Y. (Aug 2009). "Thyroidization in renal allografts.". Clin Transplant 23 Suppl 20: 6-9. doi:10.1111/j.1399-0012.2009.01001.x. PMID 19594588.