Difference between revisions of "End-stage kidney"

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#redirect [[Medical_kidney_diseases#End-stage_kidney]]
#redirect [[Medical_kidney_diseases#End-stage_kidney]]
===General===
*Many end-stage renal disease (ESRD) kidneys have a similar appearance.
**Notable exception: polycystic kidney diseases have distinctive appearance, e.g. [[ADPKD]].
===Gross===
*Small kidneys.
*Thinned renal cortex.
*+/-Dilated renal calyces.
*+/-Cysts.
Note:
*Normal (adult) kidneys are ~11 cm from pole-to-pole.<ref name=pmid20030823>{{Cite journal  | last1 = Glodny | first1 = B. | last2 = Unterholzner | first2 = V. | last3 = Taferner | first3 = B. | last4 = Hofmann | first4 = KJ. | last5 = Rehder | first5 = P. | last6 = Strasak | first6 = A. | last7 = Petersen | first7 = J. | title = Normal kidney size and its influencing factors - a 64-slice MDCT study of 1.040 asymptomatic patients. | journal = BMC Urol | volume = 9 | issue =  | pages = 19 | month =  | year = 2009 | doi = 10.1186/1471-2490-9-19 | PMID = 20030823 | URL = http://www.biomedcentral.com/1471-2490/9/19 }}</ref>
===Microscopic===
Features:
*Global sclerosis of the glomeruli.
*Interstitial fibrosis.
*+/-Thyroidization - colloid-like hyaline cast formation that impart an appearance that mimics the [[thyroid gland]]:<ref name=pmid19594588>{{Cite journal  | last1 = Ito | first1 = S. | last2 = Kobayashi | first2 = A. | last3 = Tsuchiya | first3 = T. | last4 = Moriyama | first4 = Y. | last5 = Kikuchi | first5 = M. | last6 = Deguchi | first6 = T. | last7 = Yamaguchi | first7 = Y. | title = Thyroidization in renal allografts. | journal = Clin Transplant | volume = 23 Suppl 20 | issue =  | pages = 6-9 | month = Aug | year = 2009 | doi = 10.1111/j.1399-0012.2009.01001.x | PMID = 19594588 }}</ref>
**Typical of [[chronic pyelonephritis]] and obstructive nephropathy.
Image:
*[http://library.med.utah.edu/WebPath/RENAHTML/RENAL108.html Thyroidization of the kidney (utah.edu)].
==See also==
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]

Revision as of 00:03, 12 January 2014

General

  • Many end-stage renal disease (ESRD) kidneys have a similar appearance.
    • Notable exception: polycystic kidney diseases have distinctive appearance, e.g. ADPKD.

Gross

  • Small kidneys.
  • Thinned renal cortex.
  • +/-Dilated renal calyces.
  • +/-Cysts.

Note:

  • Normal (adult) kidneys are ~11 cm from pole-to-pole.[1]

Microscopic

Features:

  • Global sclerosis of the glomeruli.
  • Interstitial fibrosis.
  • +/-Thyroidization - colloid-like hyaline cast formation that impart an appearance that mimics the thyroid gland:[2]

Image:

See also

References

  1. Glodny, B.; Unterholzner, V.; Taferner, B.; Hofmann, KJ.; Rehder, P.; Strasak, A.; Petersen, J. (2009). "Normal kidney size and its influencing factors - a 64-slice MDCT study of 1.040 asymptomatic patients.". BMC Urol 9: 19. doi:10.1186/1471-2490-9-19. PMID 20030823.
  2. Ito, S.; Kobayashi, A.; Tsuchiya, T.; Moriyama, Y.; Kikuchi, M.; Deguchi, T.; Yamaguchi, Y. (Aug 2009). "Thyroidization in renal allografts.". Clin Transplant 23 Suppl 20: 6-9. doi:10.1111/j.1399-0012.2009.01001.x. PMID 19594588.