Embryonal tumour with abundant neuropil and true rosettes

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Embryonal tumour with abundant neuropil and true rosettes, abbreviated ETANTR, is a very rare neuropathology tumour reported only in children. It is currently not listed in the WHO CNS tumour classification. There is consens, to group this entity together with ependymoblastomas under the umbrella term embryonal tumour with multilayered rosettes (ETMR).[1]


  • Super rare.
  • Reported only in children <4 years old.[2]
  • First description in 2000 by Charles Eberhart. [3]





See also


  1. Paulus, W.; Kleihues, P. (Aug 2010). "Genetic profiling of CNS tumors extends histological classification.". Acta Neuropathol 120 (2): 269-70. doi:10.1007/s00401-010-0710-1. PMID 20532895.
  2. 2.0 2.1 Wippold FJ, Perry A (March 2006). "Neuropathology for the neuroradiologist: rosettes and pseudorosettes". AJNR Am J Neuroradiol 27 (3): 488–92. PMID 16551982.
  3. Eberhart, CG.; Brat, DJ.; Cohen, KJ.; Burger, PC.. "Pediatric neuroblastic brain tumors containing abundant neuropil and true rosettes.". Pediatr Dev Pathol 3 (4): 346-52. PMID 10890250.
  4. Ferri Niguez, B.; Martínez-Lage, JF.; Almagro, MJ.; Fuster, JL.; Serrano, C.; Torroba, MA.; Sola, J. (Aug 2010). "Embryonal tumor with abundant neuropil and true rosettes (ETANTR): a new distinctive variety of pediatric PNET: a case-based update.". Childs Nerv Syst 26 (8): 1003-8. doi:10.1007/s00381-010-1179-x. PMID 20499240.