Difference between revisions of "Electron microscopy"
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*[http://media.photobucket.com/image/birbeck+granules+/cat_at_uw/Annotated%2520Remembrances/BirbeckGranules.jpg Birbeck granules (photobucket.com)]. | *[http://media.photobucket.com/image/birbeck+granules+/cat_at_uw/Annotated%2520Remembrances/BirbeckGranules.jpg Birbeck granules (photobucket.com)]. | ||
**Usually... only the handle of the tennis racket is well seen. | **Usually... only the handle of the tennis racket is well seen. | ||
==Malignant mesothelioma== | |||
{{Main|Malignant mesothelioma}} | |||
Several EM features can be useful to distinguish mesothelioma from adenocarcinoma:<ref name=pmid6287872>{{Cite journal | last1 = Warhol | first1 = MJ. | last2 = Hickey | first2 = WF. | last3 = Corson | first3 = JM. | title = Malignant mesothelioma: ultrastructural distinction from adenocarcinoma. | journal = Am J Surg Pathol | volume = 6 | issue = 4 | pages = 307-14 | month = Jun | year = 1982 | doi = | PMID = 6287872 }}</ref> | |||
{| class="wikitable sortable" | |||
!Tumour\Feature | |||
!Length/diameter of microvilli | |||
!Intermediate filaments | |||
!Complexity of microvilli | |||
!Microvillous rootltes | |||
!Myelin figures | |||
|- | |||
|Mesothelioma | |||
| 11.9 +/-5.87 | |||
| 2.8 +/-1.63 | |||
| +/- high complexity | |||
| - | |||
| - | |||
|- | |||
|Adenocarcinoma | |||
| 5.87 +/-2.3 | |||
| 0.4 +/- 0.61 | |||
| not complex | |||
| -/+ | |||
| -/+ | |||
|} | |||
==See also== | ==See also== | ||
Revision as of 01:06, 4 May 2012
This article collection stuffs about electron microscopy. It is commonly abbreviated EM.
Glycogen
Appearance:
- Cytoplasmic, electron dense, not bound by a membrane.
Seen in:
Tubuloreticular inclusions
Abbreviated TRIs.
Appearance:
- Undulating tubules in the smooth ER, usu. perinuclear.[1]
Seen in:
Melanosomes
Appearance:
- Membrane bound, sausage-like shape.
Image(s):
Seen in:
Dense-core granule
- AKA neurosecretory granules
Appearance:[2]
- Round membrane bound, granular core.
- Size: 100-400 nm.
Image(s):
Seen in:
Birbeck granules
- Seen in Langerhans cell histiocytosis.
Appearance:
- Electron dense, cytoplasmic tennis racket-like body.
Image(s):
- Birbeck granules (photobucket.com).
- Usually... only the handle of the tennis racket is well seen.
Malignant mesothelioma
Main article: Malignant mesothelioma
Several EM features can be useful to distinguish mesothelioma from adenocarcinoma:[3]
| Tumour\Feature | Length/diameter of microvilli | Intermediate filaments | Complexity of microvilli | Microvillous rootltes | Myelin figures |
|---|---|---|---|---|---|
| Mesothelioma | 11.9 +/-5.87 | 2.8 +/-1.63 | +/- high complexity | - | - |
| Adenocarcinoma | 5.87 +/-2.3 | 0.4 +/- 0.61 | not complex | -/+ | -/+ |
See also
References
- ↑ Stoltenburg-Didinger G, Genth E (June 2009). "[Dermatomyositis]" (in German). Z Rheumatol 68 (4): 287–94. doi:10.1007/s00393-008-0398-y. PMID 19330338.
- ↑ URL: http://www.pathologyimagesinc.com/emhandbook/diagn-organelles-section/organelle-pages/neuroendo-granules.html. Accessed on: 11 February 2011.
- ↑ Warhol, MJ.; Hickey, WF.; Corson, JM. (Jun 1982). "Malignant mesothelioma: ultrastructural distinction from adenocarcinoma.". Am J Surg Pathol 6 (4): 307-14. PMID 6287872.