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Difference between revisions of "Disseminated oligodendroglial-like leptomeningeal tumour"
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Disseminated oligodendroglial-like leptomeningeal tumour (view source)
Revision as of 10:14, 12 November 2020
, 10:14, 12 November 2020Update -> Change in name
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Jensflorian (talk | contribs) (Update -> Change in name) |
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''' | '''Diffuse leptomeningeal glioneuronal tumour''' (abbreviated DLGNT) is a [[neuropathology tumour]] related to [[pilocytic astrocytoma]]. The future WHO classification of CNS tumours will include it as separate entity. | ||
==General== | ==General== | ||
Features: | Features: | ||
*Currently no WHO grade assigned. | *Currently no WHO grade assigned. | ||
* Previously known as '''Disseminated oligodendroglial-like leptomeningeal tumour''' (abbreviated DOLN) | |||
*Low-grade lesion but anaplastic progression reported. | *Low-grade lesion but anaplastic progression reported. | ||
*AKA "diffuse leptomeningeal glioneural tumor" or "disseminated oligodendroglial-like leptomeningeal tumor of childhood" (DOGLT).<ref>{{Cite journal | last1 = Preuss | first1 = M. | last2 = Christiansen | first2 = H. | last3 = Merkenschlager | first3 = A. | last4 = Hirsch | first4 = FW. | last5 = Kiess | first5 = W. | last6 = Müller | first6 = W. | last7 = Kästner | first7 = S. | last8 = Henssler | first8 = A. | last9 = Pekrun | first9 = A. | title = Disseminated oligodendroglial-like leptomeningeal tumors: preliminary diagnostic and therapeutic results for a novel tumor entity [corrected]. | journal = J Neurooncol | volume = 124 | issue = 1 | pages = 65-74 | month = Aug | year = 2015 | doi = 10.1007/s11060-015-1735-z | PMID = 25672644 }}</ref> | *AKA "diffuse leptomeningeal glioneural tumor" or "disseminated oligodendroglial-like leptomeningeal tumor of childhood" (DOGLT).<ref>{{Cite journal | last1 = Preuss | first1 = M. | last2 = Christiansen | first2 = H. | last3 = Merkenschlager | first3 = A. | last4 = Hirsch | first4 = FW. | last5 = Kiess | first5 = W. | last6 = Müller | first6 = W. | last7 = Kästner | first7 = S. | last8 = Henssler | first8 = A. | last9 = Pekrun | first9 = A. | title = Disseminated oligodendroglial-like leptomeningeal tumors: preliminary diagnostic and therapeutic results for a novel tumor entity [corrected]. | journal = J Neurooncol | volume = 124 | issue = 1 | pages = 65-74 | month = Aug | year = 2015 | doi = 10.1007/s11060-015-1735-z | PMID = 25672644 }}</ref> | ||
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* [[Oligodendroglioma]]-like cells with low-mitotic activity. | * [[Oligodendroglioma]]-like cells with low-mitotic activity. | ||
* Rare ganglion/ganglioid cells. | * Rare ganglion/ganglioid cells. | ||
* Ocassionally eosinophilic granular bodies and Rosenthal fibers. | |||
* Infiltrative growth pattern. | * Infiltrative growth pattern. | ||
* Variable mitotic activity. | * Variable mitotic activity. | ||