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Difference between revisions of "Diffuse large B-cell lymphoma"
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Diffuse large B-cell lymphoma (view source)
Revision as of 14:29, 3 December 2012
, 14:29, 3 December 2012prelim
m (→Differential diagnosis: +gray zone lymphoma) |
(prelim) |
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**Can be assessed with an [[ISH]] break apart probe. | **Can be assessed with an [[ISH]] break apart probe. | ||
*Translocation typical of [[follicular lymphoma]]: t(14;18)(q32;q21)/IGH-BCL2.<ref name=pmid18359244>{{cite journal |author=Vitolo U, Ferreri AJ, Montoto S |title=Follicular lymphomas |journal=Crit. Rev. Oncol. Hematol. |volume=66 |issue=3 |pages=248–61 |year=2008 |month=June |pmid=18359244 |doi=10.1016/j.critrevonc.2008.01.014 |url=}}</ref> | *Translocation typical of [[follicular lymphoma]]: t(14;18)(q32;q21)/IGH-BCL2.<ref name=pmid18359244>{{cite journal |author=Vitolo U, Ferreri AJ, Montoto S |title=Follicular lymphomas |journal=Crit. Rev. Oncol. Hematol. |volume=66 |issue=3 |pages=248–61 |year=2008 |month=June |pmid=18359244 |doi=10.1016/j.critrevonc.2008.01.014 |url=}}</ref> | ||
==Sign out== | |||
<pre> | |||
RETROPERITONEAL MASS, RIGHT, CORE BIOPSIES: | |||
- DIFFUSE LARGE B-CELL LYMPHOMA. | |||
COMMENT: | |||
The tumour consists of cells approximately 2x the size of mature lymphocytes. Mature lymphocytes are intermixed with the tumour. There is no gland formation. Follicle formation is not apparent. | |||
</pre> | |||
===Preliminary=== | |||
<pre> | |||
RETROPERITONEAL MASS, LEFT, CORE BIOPSIES: | |||
- MORPHOLOGICALLY CONSISTENT WITH LARGE CELL LYMPHOMA -- PENDING IHC. | |||
COMMENT: | |||
Tumour cells: size ~2x mature lymphocyte, small nucleoli present, moderate | |||
quantity of grey/basophilic cytoplasm. | |||
Cells intermixed with tumour: mature lymphocytes. | |||
Architecture: no gland formation, discohesive, no follicles apparent. | |||
</pre> | |||
==See also== | ==See also== | ||