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Difference between revisions of "Desmoplastic small round cell tumour"
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Desmoplastic small round cell tumour (view source)
Revision as of 11:10, 21 January 2020
, 11:10, 21 January 2020→IHC: WT nuclear + CAM5.2
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Jensflorian (talk | contribs) (→IHC: WT nuclear + CAM5.2) |
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*Typically retroperitoneal. | *Typically retroperitoneal. | ||
*Poor prognosis. | *Poor prognosis. | ||
==Clinics== | |||
*Rare cases in the CNS reported. | |||
==Microscopic== | ==Microscopic== | ||
| Line 63: | Line 66: | ||
==IHC== | ==IHC== | ||
Features: | Features: | ||
*AE1/AE3 +ve. | *[[AE1/AE3]] +ve. | ||
*Desmin +ve. | *CAM5.2 usu -ve. | ||
*EMA +ve. | *Desmin +ve (strongly). | ||
*[[EMA]] +ve. | |||
*Actin -ve. | *Actin -ve. | ||
* | *[[WT-1]] (N-terminal) -ve. | ||
* | *[[WT-1]] (C-terminal) +ve (nuclear staining). | ||
*CD57 +ve. | *CD57 +ve. | ||
*[[Synaptophysin]] focal, patchy +ve. | |||
==Molecular== | ==Molecular== | ||
| Line 77: | Line 82: | ||
*[[Soft tissue lesions]]. | *[[Soft tissue lesions]]. | ||
*[[Small round cell tumours]]. | *[[Small round cell tumours]]. | ||
*[[Stromal desmoplasia]]. | |||
==References== | ==References== | ||
| Line 82: | Line 88: | ||
[[Category:Soft tissue lesions]] | [[Category:Soft tissue lesions]] | ||
[[Category:Neuropathology]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||