Desmoplasia
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Desmoplasia, also desmoplastic response and desmoplastic stromal response, is a stromal change associated with cancer. It is a finding that in the context of dysplasia supports a diagnosis of invasion.
Microscopic
Feature:[1]
- Large (plump) spindle cells with relatively pale nuclei.
- Increased cellular density.
- Edema - pale spaces between the cells.
DDx:
Image:
See also
References
- ↑ Weedman Molavi, Diana (2008). The Practice of Surgical Pathology: A Beginner's Guide to the Diagnostic Process (1st ed.). Springer. pp. 15. ISBN 978-0387744858.