Difference between revisions of "Dermatopathic lymphadenopathy"

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{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Dermatopathic_lymphadenopathy_-_high_mag.jpg
| Width      =
| Caption    = Dermatopathic lymphadenopathy. [[H&E stain]].
| Micro      = sinus histiocytosis with melanin pigment, esoinophils, plasma cells
| Subtypes  =
| LMDDx      = [[malignant melanoma]], [[sinus histiocytosis]], [[Hodgkin lymphoma]]
| Stains    = [[Fontana-Masson stain]]
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = [[lymph node]] - see ''[[lymph node pathology]]''
| Assdx      = T-cell lymphoma
| Syndromes  =
| Clinicalhx =
| Signs      = enlarged lymph node
| Symptoms  =
| Prevalence = uncommon
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    = other cause of lymphadenopathy
}}
'''Dermatopathic lymphadenopathy''', abbreviated '''DL''', is a rare [[lymph node pathology|pathology of the lymph nodes]].
'''Dermatopathic lymphadenopathy''', abbreviated '''DL''', is a rare [[lymph node pathology|pathology of the lymph nodes]].


==General==
==General==
*Lymphadenopathy associated with a skin lesion - '''key feature'''.
*Lymphadenopathy associated with a [[skin]] lesion.
*May be benign ''or'' malignant (e.g. T-cell lymphoma).
**May not always be true.<ref name=pmid3178430>{{Cite journal  | last1 = Gould | first1 = E. | last2 = Porto | first2 = R. | last3 = Albores-Saavedra | first3 = J. | last4 = Ibe | first4 = MJ. | title = Dermatopathic lymphadenitis. The spectrum and significance of its morphologic features. | journal = Arch Pathol Lab Med | volume = 112 | issue = 11 | pages = 1145-50 | month = Nov | year = 1988 | doi =  | PMID = 3178430 }}</ref>
*Benign in itself.<ref name=pmid17176922>{{Cite journal  | last1 = Westhoff | first1 = TH. | last2 = Loddenkemper | first2 = C. | last3 = Hörl | first3 = MP. | last4 = Schmidt | first4 = S. | last5 = Anagnostopoulos | first5 = I. | last6 = Hummel | first6 = M. | last7 = Zidek | first7 = W. | last8 = van der Giet | first8 = M. | title = Dermatopathic lymphadenopathy: a differential diagnosis of enlarged lymph nodes in uremic pruritus. | journal = Clin Nephrol | volume = 66 | issue = 6 | pages = 472-5 | month = Dec | year = 2006 | doi =  | PMID = 17176922 }}</ref>
**May be associated with a malignancy - esp. T-cell lymphoma.<ref name=pmid5341844>{{Cite journal  | last1 = Cooper | first1 = RA. | last2 = Dawson | first2 = PJ. | last3 = Rambo | first3 = ON. | title = Dermatopathic lymphadenopathy a clinicopathologic analysis of lymph node biopsy over a fifteen-year period. | journal = Calif Med | volume = 106 | issue = 3 | pages = 170-5 | month = Mar | year = 1967 | doi =  | PMID = 5341844 }}
</ref><ref name=pmid15173917>{{Cite journal  | last1 = Kojima | first1 = M. | last2 = Nakamura | first2 = S. | last3 = Itoh | first3 = H. | last4 = Yamane | first4 = Y. | last5 = Shimizu | first5 = K. | last6 = Murayama | first6 = K. | last7 = Ohno | first7 = Y. | last8 = Tanaka | first8 = H. | last9 = Sugihara | first9 = S. | title = Clinical implication of dermatopathic lymphadenopathy among Japanese: a report of 19 cases. | journal = Int J Surg Pathol | volume = 12 | issue = 2 | pages = 127-32 | month = Apr | year = 2004 | doi =  | PMID = 15173917 }}</ref>


==Microscopic==
==Microscopic==
48,474

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