48,474
edits
(5 intermediate revisions by the same user not shown) | |||
Line 1: | Line 1: | ||
{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Dermatopathic_lymphadenopathy_-_high_mag.jpg | |||
| Width = | |||
| Caption = Dermatopathic lymphadenopathy. [[H&E stain]]. | |||
| Micro = sinus histiocytosis with melanin pigment, esoinophils, plasma cells | |||
| Subtypes = | |||
| LMDDx = [[malignant melanoma]], [[sinus histiocytosis]], [[Hodgkin lymphoma]] | |||
| Stains = [[Fontana-Masson stain]] | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[lymph node]] - see ''[[lymph node pathology]]'' | |||
| Assdx = T-cell lymphoma | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = enlarged lymph node | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = other cause of lymphadenopathy | |||
}} | |||
'''Dermatopathic lymphadenopathy''', abbreviated '''DL''', is a rare [[lymph node pathology|pathology of the lymph nodes]]. | '''Dermatopathic lymphadenopathy''', abbreviated '''DL''', is a rare [[lymph node pathology|pathology of the lymph nodes]]. | ||
==General== | ==General== | ||
*Lymphadenopathy associated with a skin lesion - | *Lymphadenopathy associated with a [[skin]] lesion. | ||
*May be | **May not always be true.<ref name=pmid3178430>{{Cite journal | last1 = Gould | first1 = E. | last2 = Porto | first2 = R. | last3 = Albores-Saavedra | first3 = J. | last4 = Ibe | first4 = MJ. | title = Dermatopathic lymphadenitis. The spectrum and significance of its morphologic features. | journal = Arch Pathol Lab Med | volume = 112 | issue = 11 | pages = 1145-50 | month = Nov | year = 1988 | doi = | PMID = 3178430 }}</ref> | ||
*Benign in itself.<ref name=pmid17176922>{{Cite journal | last1 = Westhoff | first1 = TH. | last2 = Loddenkemper | first2 = C. | last3 = Hörl | first3 = MP. | last4 = Schmidt | first4 = S. | last5 = Anagnostopoulos | first5 = I. | last6 = Hummel | first6 = M. | last7 = Zidek | first7 = W. | last8 = van der Giet | first8 = M. | title = Dermatopathic lymphadenopathy: a differential diagnosis of enlarged lymph nodes in uremic pruritus. | journal = Clin Nephrol | volume = 66 | issue = 6 | pages = 472-5 | month = Dec | year = 2006 | doi = | PMID = 17176922 }}</ref> | |||
**May be associated with a malignancy - esp. T-cell lymphoma.<ref name=pmid5341844>{{Cite journal | last1 = Cooper | first1 = RA. | last2 = Dawson | first2 = PJ. | last3 = Rambo | first3 = ON. | title = Dermatopathic lymphadenopathy a clinicopathologic analysis of lymph node biopsy over a fifteen-year period. | journal = Calif Med | volume = 106 | issue = 3 | pages = 170-5 | month = Mar | year = 1967 | doi = | PMID = 5341844 }} | |||
</ref><ref name=pmid15173917>{{Cite journal | last1 = Kojima | first1 = M. | last2 = Nakamura | first2 = S. | last3 = Itoh | first3 = H. | last4 = Yamane | first4 = Y. | last5 = Shimizu | first5 = K. | last6 = Murayama | first6 = K. | last7 = Ohno | first7 = Y. | last8 = Tanaka | first8 = H. | last9 = Sugihara | first9 = S. | title = Clinical implication of dermatopathic lymphadenopathy among Japanese: a report of 19 cases. | journal = Int J Surg Pathol | volume = 12 | issue = 2 | pages = 127-32 | month = Apr | year = 2004 | doi = | PMID = 15173917 }}</ref> | |||
==Microscopic== | ==Microscopic== |
edits