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Difference between revisions of "Degenerative disc disease"
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
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'''Degenerative disc disease''', abbreviated '''[[DDD]]''', is a common [[ditzel]], typically generated in the course of a discectomy operation. | '''Degenerative disc disease''', abbreviated '''[[DDD]]''', is a common [[ditzel]], typically generated in the course of a discectomy operation. | ||
'' | ''Sciatica'',<ref name=pmid26023617>{{Cite journal | last1 = Suthar | first1 = P. | last2 = Patel | first2 = R. | last3 = Mehta | first3 = C. | last4 = Patel | first4 = N. | title = MRI evaluation of lumbar disc degenerative disease. | journal = J Clin Diagn Res | volume = 9 | issue = 4 | pages = TC04-9 | month = Apr | year = 2015 | doi = 10.7860/JCDR/2015/11927.5761 | PMID = 26023617 }}</ref> ''vertebral disc'' and ''discectomy'' redirect here. | ||
==General== | ==General== | ||
*Herniated disc - causes back pain. | *Herniated disc - causes back pain. | ||
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*+/-Synovium with or without proliferation.<ref name=pmid16393686/> | *+/-Synovium with or without proliferation.<ref name=pmid16393686/> | ||
*+/-Neovascularization of disc material.<ref name=pmid16393686/> | *+/-Neovascularization of disc material.<ref name=pmid16393686/> | ||
*Hemosiderin deposits (trauma or previous surgery). | |||
DDx: | DDx: | ||
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*Malignancy - very rare if not suspected. | *Malignancy - very rare if not suspected. | ||
**''Not'' reported in a series of 985 specimens.<ref name=pmid16393686/> | **''Not'' reported in a series of 985 specimens.<ref name=pmid16393686/> | ||
** Unexpected malignancy in 2 of 2177 specimens.<ref name=pmid16506461>{{Cite journal | last1 = Hasselblatt | first1 = M. | last2 = Maintz | first2 = D. | last3 = Goll | first3 = T. | last4 = Wildförster | first4 = U. | last5 = Schul | first5 = C. | last6 = Paulus | first6 = W. | title = Frequency of unexpected and important histopathological findings in routine intervertebral disc surgery. | journal = J Neurosurg Spine | volume = 4 | issue = 1 | pages = 20-3 | month = Jan | year = 2006 | doi = 10.3171/spi.2006.4.1.20 | PMID = 16506461 }}</ref> | |||
===Images=== | ===Images=== | ||
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==Sign out== | ==Sign out== | ||
<pre> | |||
Disc Material (L4-L5 Disc), Excision: | |||
- Consistent with disc material (gross only). | |||
</pre> | |||
<pre> | |||
Disc Material (Left L5-S1 Disc), Excision: | |||
- Consistent with disc material (gross only). | |||
</pre> | |||
Note: | |||
*May be [[gross only]] specimens; a minority of institutions handle these specimens this way.<ref name=pmid10050786>{{Cite journal | last1 = Zarbo | first1 = RJ. | last2 = Nakhleh | first2 = RE. | title = Surgical pathology specimens for gross examination only and exempt from submission: a College of American Pathologists Q-Probes study of current policies in 413 institutions. | journal = Arch Pathol Lab Med | volume = 123 | issue = 2 | pages = 133-9 | month = Feb | year = 1999 | doi = 10.1043/0003-9985(1999)1230133:SPSFGE2.0.CO;2 | PMID = 10050786 }}</ref> | |||
**It is suggested that gross only specimens should have no history or suspicion of malignancy - based on the surgical note, available pathology and imaging. | |||
===Block letters=== | |||
<pre> | <pre> | ||
CERVICAL DISC, DISCECTOMY: | CERVICAL DISC, DISCECTOMY: | ||