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DOG1 is a common immunostain classically used to diagnosis gastrointestinal stromal tumour.


Occasional positive


  • There are different commercially available clones for DOG1 (DOG1.1 and K9). The sensitivity and specificity are not the same.[3]

See also


  1. 1.0 1.1 1.2 1.3 Miettinen, M.; Wang, ZF.; Lasota, J. (Sep 2009). "DOG1 antibody in the differential diagnosis of gastrointestinal stromal tumors: a study of 1840 cases.". Am J Surg Pathol 33 (9): 1401-8. doi:10.1097/PAS.0b013e3181a90e1a. PMID 19606013.
  2. 2.0 2.1 Swalchick, W.; Shamekh, R.; Bui, MM. (Oct 2015). "Is DOG1 Immunoreactivity Specific to Gastrointestinal Stromal Tumor?". Cancer Control 22 (4): 498-504. PMID 26678977.
  3. Lopes, LF.; West, RB.; Bacchi, LM.; van de Rijn, M.; Bacchi, CE. (Jul 2010). "DOG1 for the diagnosis of gastrointestinal stromal tumor (GIST): Comparison between 2 different antibodies.". Appl Immunohistochem Mol Morphol 18 (4): 333-7. doi:10.1097/PAI.0b013e3181d27ec8. PMID 20571340.