Difference between revisions of "Cytokeratin 7"

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*Prostate.<ref name=pmid11007036/>
*Prostate.<ref name=pmid11007036/>
*Thymus.<ref name=pmid11007036/>
*Thymus.<ref name=pmid11007036/>
*[[Squamous cell carcinoma]].
*[[Squamous cell carcinoma]].


Notes:
Notes:
* ‡ Most other common types are CK7 +ve ([[papillary RCC]], [[chromophobe RCC]], [[clear cell papillary RCC]])  
* ‡ Most other common types are CK7 +ve ([[papillary RCC]], [[chromophobe RCC]], [[clear cell papillary RCC]])  
 
* † May be positive. In one series of head and neck SCC: conventional SCC 7 +ve of 34 cases, [[basaloid squamous cell carcinoma]] 24 +ve of 45 cases.<ref name=pmid20614292>{{Cite journal  | last1 = Winters | first1 = R. | last2 = Naud | first2 = S. | last3 = Evans | first3 = MF. | last4 = Trotman | first4 = W. | last5 = Kasznica | first5 = P. | last6 = Elhosseiny | first6 = A. | title = Ber-EP4, CK1, CK7 and CK14 are useful markers for basaloid squamous carcinoma: a study of 45 cases. | journal = Head Neck Pathol | volume = 2 | issue = 4 | pages = 265-71 | month = Dec | year = 2008 | doi = 10.1007/s12105-008-0089-7 | PMID = 20614292 }}</ref>
<gallery>
<gallery>
File:Adenocarcinoma - CK7 immunostain (5762463282).jpg | Adenocarcinoma of the lung (WC/Yale Rosen)
File:Adenocarcinoma - CK7 immunostain (5762463282).jpg | Adenocarcinoma of the lung (WC/Yale Rosen)

Revision as of 19:09, 23 March 2016

CK7 immunostain in acinar adenocarcinoma of the lung.

Cytokeratin 7, also keratin 7 and CK7, is a common low molecular keratin and a very common immunostain.[1]

Positive

Classic positive

  • Pancreas.
  • Stomach.
  • Urothelial carcinoma.
  • Esophageal adenocarcinoma.

Negative

Classic negative

Notes:

See also

References

  1. 1.0 1.1 1.2 1.3 1.4 Chu, P.; Wu, E.; Weiss, LM. (Sep 2000). "Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases.". Mod Pathol 13 (9): 962-72. doi:10.1038/modpathol.3880175. PMID 11007036.
  2. Winters, R.; Naud, S.; Evans, MF.; Trotman, W.; Kasznica, P.; Elhosseiny, A. (Dec 2008). "Ber-EP4, CK1, CK7 and CK14 are useful markers for basaloid squamous carcinoma: a study of 45 cases.". Head Neck Pathol 2 (4): 265-71. doi:10.1007/s12105-008-0089-7. PMID 20614292.