Cytokeratin 20

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Cytokeratin 20, abbreviated CK20, is a commonly used immunostain. It is also known as keratin 20.

CK20 staining in small intestine.


CK20 positive and CK7 negative

Partially CK20 positive

CK20 positive and CK7 positive


See also


  1. Chu, P.; Wu, E.; Weiss, LM. (Sep 2000). "Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases.". Mod Pathol 13 (9): 962-72. doi:10.1038/modpathol.3880175. PMID 11007036.
  2. Eschbacher, JM.; Coons, SW. (2006). "Cytokeratin CK20 is a sensitive marker for Crooke's cells and the early cytoskeletal changes associated with hypercortisolism within pituitary corticotrophs.". Endocr Pathol 17 (4): 365-76. PMID 17525485.