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Difference between revisions of "Cytokeratin 20"
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==Positive== | ==Positive== | ||
===CK20 positive and CK7 negative=== | |||
*Virtually all [[colorectal carcinoma]]s.<ref name=pmid11007036>{{Cite journal | last1 = Chu | first1 = P. | last2 = Wu | first2 = E. | last3 = Weiss | first3 = LM. | title = Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. | journal = Mod Pathol | volume = 13 | issue = 9 | pages = 962-72 | month = Sep | year = 2000 | doi = 10.1038/modpathol.3880175 | PMID = 11007036 }}</ref> | *Virtually all [[colorectal carcinoma]]s.<ref name=pmid11007036>{{Cite journal | last1 = Chu | first1 = P. | last2 = Wu | first2 = E. | last3 = Weiss | first3 = LM. | title = Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. | journal = Mod Pathol | volume = 13 | issue = 9 | pages = 962-72 | month = Sep | year = 2000 | doi = 10.1038/modpathol.3880175 | PMID = 11007036 }}</ref> | ||
*[[Merkel cell carcinoma]] - perinuclear dot-like pattern. | *[[Merkel cell carcinoma]] - perinuclear dot-like pattern. | ||
*[[Eosinophilic, solid and cystic renal cell carcinoma]] - an evolving entity. | |||
===Partially CK20 positive=== | |||
*Corticotrophic [[pituitary adenoma]]s and [[Crooke-hyaline change]]s.<ref name=pmid17525485>{{Cite journal | last1 = Eschbacher | first1 = JM. | last2 = Coons | first2 = SW. | title = Cytokeratin CK20 is a sensitive marker for Crooke's cells and the early cytoskeletal changes associated with hypercortisolism within pituitary corticotrophs. | journal = Endocr Pathol | volume = 17 | issue = 4 | pages = 365-76 | month = | year = 2006 | doi = | PMID = 17525485 }}</ref> | |||
===CK20 positive and CK7 positive=== | |||
*Pancreatic adenocarcinoma. | |||
*Ovarian mucinous carcinoma. | |||
*Occasionally stomach adenocarcinoma, cholangiocarcinoma. | |||
*[[Urothelial carcinoma]]. | |||
*[[Esophageal adenocarcinoma]]. | |||
====Images==== | |||
<gallery> | |||
Image: Urothelial carcinoma - CK20 -- intermed mag.jpg | UCC - CK20 - intermed. mag. (WC) | |||
Image: Urothelial carcinoma - CK20 -- high mag.jpg | UCC - CK20 - high mag. (WC) | |||
</gallery> | |||
==See also== | ==See also== | ||
*[[Immunohistochemistry]]. | *[[Immunohistochemistry]]. | ||
*[[CK7]]. | |||
==References== | ==References== | ||