Difference between revisions of "Compound nevus"

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| Caption    = Compound nevus. [[H&E stain]].
| Caption    = Compound nevus. [[H&E stain]].
| Synonyms  = compound melanocytic nevus
| Synonyms  = compound melanocytic nevus
| Micro      = nests of melanocytes, melanocytes "mature" with depth, usu. no mitoses (occ. superficial), no destruction of surrounding structures, no conspicuous nucleoli, dermis '''and''' epidermis - '''key feature'''.
| Micro      = nests of melanocytes in dermis ''and'' epidermis, melanocytes "mature" with depth, usu. no mitoses (occ. superficial), no destruction of surrounding structures, no conspicuous nucleoli, no significant melanocyte enlargement
| Subtypes  =
| Subtypes  =
| LMDDx      = [[malignant melanoma]] (nevoid), [[junctional nevus]], [[intradermal nevus]], [[dysplastic nevus]]
| LMDDx      = [[malignant melanoma]] (nevoid), [[junctional nevus]], [[intradermal nevus]], [[dysplastic nevus]]
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| Other      =
| Other      =
| ClinDDx    = pigmented skin lesions
| ClinDDx    = pigmented skin lesions
| Tx        =
| Tx        = none required, may be excised for cosmetic reasons
}}
}}
'''Compound nevus''' (abbreviated '''CN'''), also '''compound melanocytic nevus''' (abbreviated '''CMN'''), is a common benign [[melanocytic lesion]].
'''Compound nevus''' (abbreviated '''CN'''), also '''compound melanocytic nevus''' (abbreviated '''CMN'''), is a common benign [[melanocytic lesion]].
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*Benign.
*Benign.
*Common.
*Common.
*Think ''[[melanoma]]''.
*Arise from [[junctional nevus|junctional nevi]] and then progress to [[intradermal nevi]].<ref>URL: [http://www.dermpedia.org/dermpedia-textbook/compound-nevus http://www.dermpedia.org/dermpedia-textbook/compound-nevus]. Accessed on: 20 May 2014.</ref>


Clinical:  
Clinical - think about [[malignant melanoma]]... it should ''not'' be like melanoma:  
*''ABCD'' = asymmetric, borders (irregular), colour (black), diameter (large).
*''ABCD'' = asymmetric, borders (irregular), colour (black), diameter (large).


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*In the dermis '''and''' epidermis - '''key feature'''.
*In the dermis '''and''' epidermis - '''key feature'''.
*+/-Adipocytes - uncommon.<ref name=pmid9810886>{{Cite journal  | last1 = Eng | first1 = W. | last2 = Cohen | first2 = PR. | title = Nevus with fat: clinical characteristics of 100 nevi containing mature adipose cells. | journal = J Am Acad Dermatol | volume = 39 | issue = 5 Pt 1 | pages = 704-11 | month = Nov | year = 1998 | doi =  | PMID = 9810886 }}</ref>
*+/-Adipocytes - uncommon.<ref name=pmid9810886>{{Cite journal  | last1 = Eng | first1 = W. | last2 = Cohen | first2 = PR. | title = Nevus with fat: clinical characteristics of 100 nevi containing mature adipose cells. | journal = J Am Acad Dermatol | volume = 39 | issue = 5 Pt 1 | pages = 704-11 | month = Nov | year = 1998 | doi =  | PMID = 9810886 }}</ref>
DDx:
*[[Malignant melanoma]] (nevoid).
*[[Dysplastic nevus]].
*[[Junctional nevus]].
*[[Intradermal nevus]].


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