48,460
edits
(6 intermediate revisions by the same user not shown) | |||
Line 5: | Line 5: | ||
| Caption = Compound nevus. [[H&E stain]]. | | Caption = Compound nevus. [[H&E stain]]. | ||
| Synonyms = compound melanocytic nevus | | Synonyms = compound melanocytic nevus | ||
| Micro = nests of melanocytes, melanocytes "mature" with depth, usu. no mitoses (occ. superficial), no destruction of surrounding structures, no conspicuous nucleoli, | | Micro = nests of melanocytes in dermis ''and'' epidermis, melanocytes "mature" with depth, usu. no mitoses (occ. superficial), no destruction of surrounding structures, no conspicuous nucleoli, no significant melanocyte enlargement | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[malignant melanoma]] (nevoid), [[junctional nevus]], [[intradermal nevus]] | | LMDDx = [[malignant melanoma]] (nevoid), [[junctional nevus]], [[intradermal nevus]], [[dysplastic nevus]] | ||
| Stains = | | Stains = | ||
| IHC = | | IHC = | ||
Line 28: | Line 28: | ||
| Other = | | Other = | ||
| ClinDDx = pigmented skin lesions | | ClinDDx = pigmented skin lesions | ||
| Tx = | | Tx = none required, may be excised for cosmetic reasons | ||
}} | }} | ||
'''Compound nevus''' (abbreviated '''CN'''), also '''compound melanocytic nevus''' (abbreviated '''CMN'''), is a common benign [[melanocytic lesion]]. | '''Compound nevus''' (abbreviated '''CN'''), also '''compound melanocytic nevus''' (abbreviated '''CMN'''), is a common benign [[melanocytic lesion]]. | ||
Line 37: | Line 37: | ||
*Benign. | *Benign. | ||
*Common. | *Common. | ||
* | *Arise from [[junctional nevus|junctional nevi]] and then progress to [[intradermal nevi]].<ref>URL: [http://www.dermpedia.org/dermpedia-textbook/compound-nevus http://www.dermpedia.org/dermpedia-textbook/compound-nevus]. Accessed on: 20 May 2014.</ref> | ||
Clinical: | Clinical - think about [[malignant melanoma]]... it should ''not'' be like melanoma: | ||
*''ABCD'' = asymmetric, borders (irregular), colour (black), diameter (large). | *''ABCD'' = asymmetric, borders (irregular), colour (black), diameter (large). | ||
Line 56: | Line 56: | ||
*In the dermis '''and''' epidermis - '''key feature'''. | *In the dermis '''and''' epidermis - '''key feature'''. | ||
*+/-Adipocytes - uncommon.<ref name=pmid9810886>{{Cite journal | last1 = Eng | first1 = W. | last2 = Cohen | first2 = PR. | title = Nevus with fat: clinical characteristics of 100 nevi containing mature adipose cells. | journal = J Am Acad Dermatol | volume = 39 | issue = 5 Pt 1 | pages = 704-11 | month = Nov | year = 1998 | doi = | PMID = 9810886 }}</ref> | *+/-Adipocytes - uncommon.<ref name=pmid9810886>{{Cite journal | last1 = Eng | first1 = W. | last2 = Cohen | first2 = PR. | title = Nevus with fat: clinical characteristics of 100 nevi containing mature adipose cells. | journal = J Am Acad Dermatol | volume = 39 | issue = 5 Pt 1 | pages = 704-11 | month = Nov | year = 1998 | doi = | PMID = 9810886 }}</ref> | ||
DDx: | |||
*[[Malignant melanoma]] (nevoid). | |||
*[[Dysplastic nevus]]. | |||
*[[Junctional nevus]]. | |||
*[[Intradermal nevus]]. | |||
===Images=== | ===Images=== |
edits