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Difference between revisions of "Complex endometrial hyperplasia"
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Complex endometrial hyperplasia (view source)
Revision as of 14:24, 2 March 2017
, 14:24, 2 March 2017→Microscopic
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| IF = | | IF = | ||
| Gross = thickened endometrium | | Gross = thickened endometrium | ||
| Grossing = | | Grossing = [[hysterectomy for endometrial hyperplasia grossing]] | ||
| Site = [[endometrium]] - see ''[[endometrial hyperplasia]] | | Site = [[endometrium]] - see ''[[endometrial hyperplasia]] | ||
| Assdx = [[obesity]] | | Assdx = [[obesity]], [[endometrium with squamous morules]] | ||
| Syndromes = | | Syndromes = | ||
| Clinicalhx = usu. premenopausal or perimenopausal | | Clinicalhx = usu. premenopausal or perimenopausal | ||
| Line 69: | Line 69: | ||
DDx: | DDx: | ||
*Artifactual gland crowding due to fragmentation - white space around the glands. | *Artifactual gland crowding due to fragmentation - white space around the glands. | ||
*Endometrial gland coiling - no sharp transition, moderate stroma between the glands horizontally. | *[[Endometrial gland coiling]] - no sharp transition, moderate stroma between the glands horizontally. | ||
*[[Endometrioid endometrial carcinoma]] - see ''[[endometrial carcinoma versus complex endometrial hyperplasia]]''. | *[[Endometrioid endometrial carcinoma]] - see ''[[endometrial carcinoma versus complex endometrial hyperplasia]]''. | ||
*Benign papillary proliferation of the endometrium.<ref name=pmid23211295>{{Cite journal | last1 = Ip | first1 = PP. | last2 = Irving | first2 = JA. | last3 = McCluggage | first3 = WG. | last4 = Clement | first4 = PB. | last5 = Young | first5 = RH. | title = Papillary proliferation of the endometrium: a clinicopathologic study of 59 cases of simple and complex papillae without cytologic atypia. | journal = Am J Surg Pathol | volume = 37 | issue = 2 | pages = 167-77 | month = Feb | year = 2013 | doi = 10.1097/PAS.0b013e318272d428 | PMID = 23211295 }}</ref> | |||
===Endometrial carcinoma versus complex endometrial hyperplasia=== | ===Endometrial carcinoma versus complex endometrial hyperplasia=== | ||
Complex endometrial hyperplasia: | Complex endometrial hyperplasia: | ||
| Line 115: | Line 115: | ||
Image: Endometrial polyp with fused glands -- high mag.jpg | Endometrial polyp with fused glands - high mag. (WC) | Image: Endometrial polyp with fused glands -- high mag.jpg | Endometrial polyp with fused glands - high mag. (WC) | ||
</gallery> | </gallery> | ||
www: | www: | ||
*[http://www.webpathology.com/image.asp?n= | *[http://www.webpathology.com/image.asp?n=3&Case=568 Complex endometrial hyperplasia without atypia (webpathology.com)]. | ||
*[http://www.webpathology.com/image.asp?n= | *[http://www.webpathology.com/image.asp?n=4&Case=568 Complex endometrial hyperplasia without atypia (webpathology.com)]. | ||
==Sign out== | ==Sign out== | ||
| Line 175: | Line 174: | ||
for the diagnosis of endometrial carcinoma. | for the diagnosis of endometrial carcinoma. | ||
</pre> | </pre> | ||
====Micro==== | |||
=====CEH with atypia===== | |||
The sections show endometrium with atypical hyperchromatic, densely packed branching glands. The nuclei of the atypical glands focally are round, 2-3x the size of a lymphocyte, and have grey/translucent chromatin and small nucleoli. No papillary or cribriform changes are appreciated. No desmoplastic stroma is identified. | |||
==See also== | ==See also== | ||